Results 61 to 70 of about 3,277,159 (252)

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Ultrasound contrast agent delivered per os first diagnoses pharyngoesophageal tumour

open access: yesJournal of the Belgian Society of Radiology, 2013
Oral administration of ultrasound contrast agents has been described very little so far in medical literature. These agents are mainly administered intravenously and, less commonly, intracavitarily.
E Antypa   +4 more
doaj   +1 more source

Stable one-dimensional periodic waves in Kerr-type saturable and quadratic nonlinear media

open access: yes, 2005
We review the latest progress and properties of the families of bright and dark one-dimensional periodic waves propagating in saturable Kerr-type and quadratic nonlinear media.
Akhmediev N N   +35 more
core   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

Contrast Media - A Review

open access: yesJournal of Indian Academy of Oral Medicine and Radiology, 2003
When the clinical procedure alone fails to achieve accurate diagnosis, there is need to proceed from the simpler, more innocuous technique to other more complex invasive investigations. Radiography is one such simple procedure.
Syeda Arshiya, B Balaji Rao, G P Mamatha
doaj  

Phase-change chalcogenide glass metamaterial [PDF]

open access: yes, 2009
Combining metamaterials with functional media brings a new dimension to their performance. Here we demonstrate substantial resonance frequency tuning in a photonic metamaterial hybridized with an electrically/optically switchable chalcogenide glass.
B. Gholipour   +9 more
core   +1 more source

Tau acetylation at K331 has limited impact on tau pathology in vivo

open access: yesFEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto   +3 more
wiley   +1 more source

Curriculum for the Management of Contrast Media Reactions, Contrast Induced Nephropathy & Nephrogenic Systemic Fibrosis

open access: yesMedEdPORTAL, 2013
Radiologists supervising imaging studies using contrast media should have the necessary knowledge and skills to deal with adverse contrast media reactions and their appropriate management. The aim of this curriculum is to educate practicing radiologists,
Puneet Bhargava   +9 more
doaj   +1 more source

Asymptotic expansions for high-contrast elliptic equations

open access: yes, 2012
In this paper, we present a high-order expansion for elliptic equations in high-contrast media. The background conductivity is taken to be one and we assume the medium contains high (or low) conductivity inclusions. We derive an asymptotic expansion with
Calo, Victor M.   +2 more
core   +1 more source

A methionine‐lined active site governs carbocation stabilization and product specificity in a bacterial terpene synthase

open access: yesFEBS Letters, EarlyView.
This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel   +13 more
wiley   +1 more source

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