Results 71 to 80 of about 21,692,993 (303)

Bridging the Allergy–Radiology Gap in Radiocontrast Media Hypersensitivity: A Patient-Level Linkage Study on Diagnostic Stewardship and Re-Exposure Outcomes

open access: yesLife
Background/Objectives: We examined how allergy findings related to candidate-agent identification, subsequent real-world imaging and clinical outcomes. Methods: This single-centre retrospective cohort included 29 adults evaluated between January 2019 and
Meryem İrem Toksoy Şentürk   +13 more
doaj   +1 more source

DNA ligase LigE increases bacterial transformation with damaged extracellular DNA

open access: yesFEBS Letters, EarlyView.
The DNA ligase LigE from the naturally competent Gram‐negative bacterium Neisseria gonorrhoaea increases transformation with cut extracellular DNA. This process is ATP‐dependent and relies on the catalytic activity of LigE; it also requires that LigE contains an intact periplasmic localisation sequence, indicating that ligE functions in the periplasm ...
Jolyn Pan   +4 more
wiley   +1 more source

The functional role of contrast adaptation [PDF]

open access: yes, 1988
Prolonged inspection of high contrast sinewave gratings increases the contrast required to detect gratings having a similar spatial frequency and orientation. The functional role of such adaptation has, however, in the past, eluded disclosure.
Heitger, F., Greenlee, Mark W.
core   +1 more source

Curriculum for the Management of Contrast Media Reactions, Contrast Induced Nephropathy & Nephrogenic Systemic Fibrosis

open access: yesMedEdPORTAL, 2013
Radiologists supervising imaging studies using contrast media should have the necessary knowledge and skills to deal with adverse contrast media reactions and their appropriate management. The aim of this curriculum is to educate practicing radiologists,
Puneet Bhargava   +9 more
doaj   +1 more source

Going viral − Virus‐targeting nanobodies for research, diagnostics and therapy

open access: yesFEBS Letters, EarlyView.
The increasing prevalence of viral diseases represents a major threat for global human health. Nanobodies, small binding fragments derived from camelid heavy‐chain antibodies, offer versatile tools for viral research, diagnostics, and antiviral therapy.
Domenic Ebert, Ulrich Rothbauer
wiley   +1 more source

Nephrogenic systemic fibrosis and gadolinium-based contrast media: updated ESUR Contrast Medium Safety Committee guidelines

open access: yes, 2012
To update the guidelines of the Contrast Media Safety Committee (CMSC) of the European Society of Urogenital Radiology (ESUR) on nephrogenic systemic fibrosis and gadolinium-based contrast media. Topics reviewed include the history, clinical features and
Bongartz, Georg   +30 more
core   +2 more sources

Iodinated Contrast-Induced Hypothyroidism in An Infant after Enteral Contrast Enema: A Case-Report and Systematic Review

open access: yesJCRPE
Excessive iodine intake may trigger the Wolff-Chaikoff effect, which results in downregulation of thyroid hormone synthesis to prevent hyperthyroidism. Failure to recover euthyroidism after the Wolff-Chaikoff effect may be seen in infants, and especially
Adinda G. H. Pijpers   +10 more
doaj   +1 more source

How structural disorder and polyelectrolyte properties of prothymosin α enable its large interactome

open access: yesFEBS Letters, EarlyView.
In this review, complexes of the fully disordered and highly negatively charged prothymosin α are collected, described, and discussed. Linked to its poly‐electrostatic character, prothymosin α engages a large interactome through multiple different binding modes ranging from fully disordered complexes to short linear motif (SLiM)‐driven interactions ...
Ketty C. Tamburrini   +3 more
wiley   +1 more source

Contrast Media Induced Kounis Syndrome: A Case Report

open access: yesDiagnostics, 2019
Kounis syndrome is a rare anaphylactic reaction leading to coronary spasm, acute plaque rupture, or intrastent stenosis. Many types of medicine or environmental factors can potentially trigger Kounis syndrome by mast cell allergic reactions.
Da-Sen Chien   +4 more
doaj   +1 more source

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska   +13 more
wiley   +1 more source

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