Results 61 to 70 of about 8,977,078 (369)

Pharmacology, Part 5: CT and MRI Contrast Media

open access: yesJournal of Nuclear Medicine Technology, 2019
Pharmacology principles provide key understanding that underpins the clinical and research roles of nuclear medicine practitioners. The scope of practice of the nuclear medicine technologist demands knowledge and understanding of indications ...
G. Currie
semanticscholar   +1 more source

Plasmodium falciparum gametogenesis essential protein 1 (GEP1) is a transmission‐blocking target

open access: yesFEBS Letters, EarlyView.
This study shows Plasmodium falciparum GEP1 is vital for activating sexual stages of malarial parasites even independently of a mosquito factor. Knockout parasites completely fail gamete formation even when a phosphodiesterase inhibitor is added. Two single‐nucleotide polymorphisms (V241L and S263P) are found in 12%–20% of field samples.
Frederik Huppertz   +5 more
wiley   +1 more source

4‐nitrobenzoate inhibits 4‐hydroxybenzoate polyprenyltransferase in malaria parasites and enhances atovaquone efficacy

open access: yesFEBS Letters, EarlyView.
Atovaquone is an antimalarial requiring potentiation for sufficient efficacy. We pursued strategies to enhance its activity, showing that 4‐nitrobenzoate inhibits 4‐hydroxybenzoate polyprenyltransferase, decreasing ubiquinone biosynthesis. Since atovaquone competes with ubiquinol in mitochondria, 4‐nitrobenzoate facilitates its action, potentiating ...
Ignasi Bofill Verdaguer   +7 more
wiley   +1 more source

The Impact of Radiation Dose on CT‐Based Body Composition Analysis: A Large‐Animal Study

open access: yesJournal of Cachexia, Sarcopenia and Muscle
Background CT‐based body composition analysis (BCA) enables the extraction of biomarkers from routine CT data. The influence of body composition on the prognosis of different patient groups has been highlighted in recent years.
Luca Salhöfer   +10 more
doaj   +1 more source

CONTRAST-INDUCED NEPHROPATHY (CIN): A RAPID OVERVIEW FOR RISK ASSESSMENT AND PREVENTION.

open access: yesEuromediterranean Biomedical Journal, 2017
In recent years, the number of contrastographic exams has increased considerably, compared to an increase in the complications related to this type of interventional approach.
Daniele Bissacco
doaj   +1 more source

Phase-change chalcogenide glass metamaterial [PDF]

open access: yes, 2009
Combining metamaterials with functional media brings a new dimension to their performance. Here we demonstrate substantial resonance frequency tuning in a photonic metamaterial hybridized with an electrically/optically switchable chalcogenide glass.
B. Gholipour   +9 more
core   +1 more source

Organoids in pediatric cancer research

open access: yesFEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Stable one-dimensional periodic waves in Kerr-type saturable and quadratic nonlinear media

open access: yes, 2005
We review the latest progress and properties of the families of bright and dark one-dimensional periodic waves propagating in saturable Kerr-type and quadratic nonlinear media.
Akhmediev N N   +35 more
core   +1 more source

Photosynthesis under far‐red light—evolutionary adaptations and bioengineering of light‐harvesting complexes

open access: yesFEBS Letters, EarlyView.
Phototrophs evolved light‐harvesting systems adapted for efficient photon capture in habitats enriched in far‐red radiation. A subset of eukaryotic pigment‐binding proteins can absorb far‐red photons via low‐energy chlorophyll states known as red forms.
Antonello Amelii   +8 more
wiley   +1 more source

Effects of zirconia nanoparticles addition to experimental adhesives on radiopacity and microhardness

open access: yesBrazilian Journal of Oral Sciences, 2015
Aim: To evaluate the radiopacity and microhardness (KHN) of experimental dental adhesives (EX). The experimental adhesive resins of the present study were formulated based on the simplified adhesive system Ambar (FGM).
Gislaine Cristine Martins   +5 more
doaj   +1 more source

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