Results 71 to 80 of about 3,069,323 (369)

Spot‐14 and its paralog Spot‐14R regulate expression of metabolic and thermogenic pathway genes in murine brown and beige adipocytes

open access: yesFEBS Letters, EarlyView.
Spot‐14 and Spot‐14R play distinct roles in regulating metabolism in brown and beige adipocytes. While both influence lipid and glucose pathways, Spot‐14 uniquely controls thermogenic gene expression. This dual regulation balances energy storage and heat production, highlighting potential therapeutic targets for obesity and metabolic disorders. Spot 14
Lidia Itzel Castro‐Rodríguez   +3 more
wiley   +1 more source

Assessment of estimated GFR and clinical predictors of contrast induced nephropathy among diabetic patients undergoing cardiac catheterization

open access: yesThe Egyptian Heart Journal, 2015
Introduction: Contrast-induced nephropathy is a leading cause of morbidity and mortality in high-risk patients. Aim: To study different risk predictors of contrast induced nephropathy, among diabetic patients with normal serum creatinine undergoing ...
Tarek Zaki   +4 more
doaj   +1 more source

An Adaptive Contrast Enhancement Algorithm with Details Preserving [PDF]

open access: yes, 2014
This paper presents an adaptive contrastenhancement algorithm with details preserving (ACEDP) toenhance gray-scale image. Initially, the input image is classifiedinto low-, middle- or high-level image based on the gray-leveldistribution of maximum number
Isa, N. A. (Nor), Tang, J. R. (Jing)
core  

Media justice: Madeleine McCann, intermediatization and "trial by media" in the British press [PDF]

open access: yes, 2012
Three-year-old Madeleine McCann disappeared on 3 May 2007 from a holiday apartment in Portugal. Over five years and multiple investigations that failed to solve this abducted child case, Madeleine and her parents were subject to a process of relentless ...
Alexander JC   +28 more
core   +1 more source

A cellular system to study responses to a collision between the transcription complex and a protein‐bound nick in the DNA template

open access: yesFEBS Letters, EarlyView.
We present the cellular transcription‐coupled Flp‐nick system allowing the introduction of a Top1‐mimicking cleavage complex (Flpcc) at a Flp recognition target site within a controllable LacZ gene. LacZ transcription leads to the collision of RNA polymerase II (RNAPII) with Flpcc, and this causes RNAPII stalling, ubiquitination, and degradation.
Petra Herring   +6 more
wiley   +1 more source

Parameter Sigmoid Transform Contrast Enhancement for Dental Radiograph Classification and Numbering System [PDF]

open access: yes, 2015
Dental record is a method that is used to identify a person. The identification process needs a system that could recognize each individual tooth automatically.
Arifin, A. Z. (Agus)   +5 more
core  

Visualization of leukocyte transendothelial and interstitial migration using reflected light oblique transillumination in intravital video microscopy [PDF]

open access: yes, 2003
Dynamic visualization of the intravascular events leading to the extravasation of leukocytes into tissues by intravital microscopy has significantly expanded our understanding of the underlying molecular processes.
Hutter, J.   +4 more
core   +1 more source

Ion channel function of polycystin‐2/polycystin‐1 heteromer revealed by structure‐guided mutagenesis

open access: yesFEBS Letters, EarlyView.
Mutations in polycystin‐1 (PC1) or polycystin‐2 (PC2) cause autosomal‐dominant polycystic kidney disease (ADPKD). We generated a novel gain‐of‐function PC2/PC1 heteromeric ion channel by mutating pore‐blocking residues. Moreover, we demonstrated that PC2 will preferentially assemble with PC1 to form heteromeric complexes when PC1 is co‐expressed ...
Tobias Staudner   +7 more
wiley   +1 more source

Feasibility and Safety of Very-Low Contrast Combined Ringer's Solution in Optical Coherence Tomography Imaging

open access: yesFrontiers in Cardiovascular Medicine, 2022
BackgroundOptical coherence tomography (OCT) is an important modality used in coronary intervention. However, OCT requires a high amount of contrast media, limiting its extensive application in clinical practice.
Tao Chen   +29 more
doaj   +1 more source

Numerical simulation of the electromagnetic wave reflection from 2D random semi-infinite strongly scattering media [PDF]

open access: yesarXiv, 2023
Light scattering in disordered media plays an important role in various areas of applied science from biophysics to astronomy. In this paper we study two approaches to calculate scattering properties of semi-infinite densely packed media with high contrast and wavelength scale inhomogeneities by combining the Fourier Modal Method and the super-cell ...
arxiv  

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