Results 141 to 150 of about 2,583,441 (289)

Pupillographic evaluation accompanying structural and functional assessment of the optic nerve in patients with Parkinson’s disease

BMC Ophthalmology
Background To evaluate static and dynamic pupillary functions, contrast sensitivity, and retinal nerve fiber layer (RNFL) thickness in patients with Parkinson’s disease.
Erdinç Bozkurt, Ersin Muhafız, Can Emre Erdoğan, Şerif Nizamoğulları, Güvenç Toprak, Bayram Meydan   +5 more
doaj   +1 more source

The Characteristics of Quick Contrast Sensitivity Function in Keratoconus and Its Correlation with Corneal Topography. [PDF]

Ophthalmol Ther, 2023
Xian Y, Sun L, Ye Y, Zhang X, Zhao W, Shen Y, Lu ZL, Zhou X, Zhao J.   +8 more
europepmc   +1 more source

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

Molecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano, Giuseppina Minopoli, Simona Romano, Laura Marrone, Katia Aquilano, Maria Lina Tornesello, Raffaella Faraonio   +6 more
wiley   +1 more source

A novel quick contrast sensitivity function test in Chinese adults with myopia and its related parameters. [PDF]

Graefes Arch Clin Exp Ophthalmol, 2023
Ye Y, Aruma A, Zhao W, Lu ZL, Zhou X, Zhao J.   +5 more
europepmc   +1 more source

Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma

Molecular Oncology, EarlyView.
Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra, Lucca Paolo Hsu Helmich, Daniel Rodrigues de Bastos, Laura Sichero, Patrícia Savio de Araujo‐Souza, Fabio Passetti, Luisa Lina Villa   +6 more
wiley   +1 more source

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

Molecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson, Lyanne Delgado‐Coka, Natalia Marchenko, Luisa F. Escobar‐Hoyos, Kenneth R. Shroyer, Alisa Yurovsky, Trey Ideker, Gábor Balázsi, Thomas MacCarthy, Scott Powers   +9 more
wiley   +1 more source

RIPK4 function interferes with melanoma cell adhesion and metastasis

Molecular Oncology, EarlyView.
RIPK4 promotes melanoma growth and spread. RIPK4 levels increase as skin lesions progress to melanoma. CRISPR/Cas9‐mediated deletion of RIPK4 causes melanoma cells to form less compact spheroids, reduces their migratory and invasive abilities and limits tumour growth and dissemination in mouse models.
Norbert Wronski, Sławomir Lasota, Ewelina Madej, Anna A. Brożyna, Małgorzata Szczygieł, Agnieszka Harazin‐Lechowska, Jan Czerbniak, Janusz Rys, Jaroslaw Czyz, Agnieszka Wolnicka‐Glubisz   +9 more
wiley   +1 more source

Correlation of contrast sensitivity at low spatial frequencies with myopic shift in Chinese children

BMC Ophthalmology
Purpose To investigate the correlation of contrast sensitivity function (CSF) with myopic shift in Chinese children. Methods This prospective case-series study included 62 eyes (31 children) who visited the Eye and ENT Hospital of Fudan University in ...
Yuhao Ye, Fang Liu, Yiyong Xian, Meng Li, Lingling Niu, Xingtao Zhou, Jing Zhao   +6 more
doaj   +1 more source

Pre‐analytical optimization of cell‐free DNA and extracellular vesicle‐derived DNA for mutation detection in liquid biopsies

Molecular Oncology, EarlyView.
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen, Lucrezia De Santis, Bret M. Stephens, Vincent Bernard, Jörg C. Kalff, Lara Braun, Phillipp Leyendecker, Johannes Röttgen, Daniel Weissinger, Anirban Maitra, Paola A. Guerrero, Alexander Semaan   +11 more
wiley   +1 more source

Reduced contrast sensitivity function correlated with superficial retinal capillary plexus impairment in early stage of dysthyroid optic neuropathy. [PDF]

Eye Vis (Lond), 2023
Tu Y, Jin H, Xu M, Liu W, Hu X, Wang M, Ye J, Liu Z, Gao M, Hou F, Lu ZL, Wu W.   +11 more
europepmc   +1 more source