Results 161 to 170 of about 2,583,441 (289)

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

Molecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova, Michele Montrone, Uday Rangaswamy, Francesco Diversi, Irene Schiavo, Denise Ferrarini, Roberta Di Florio, Irene Longo, Michele Coscia, Nicola Zamboni, Giorgia Demontis, Lisa Veghini, Vincenzo Corbo, Remo Sanges, Paul Heppenstall   +14 more
wiley   +1 more source

Binocular Contrast Sensitivity Function in Children With Anisometropic Amblyopia. [PDF]

Invest Ophthalmol Vis Sci
Liao N, Jiang H, Qin Y, Wan M, Zhou J, Lu ZL, Yu X, Hou F.   +7 more
europepmc   +1 more source

Photopic and Mesopic Contrast Sensitivity Function in the Presence of Glare and the Effect of Filters in Young Healthy Adults. [PDF]

Front Psychol, 2021
Domínguez-Vicent A, Helghe E, Wahlberg Ramsay M, Venkataraman AP.   +3 more
europepmc   +1 more source

Does binocular disparity impact the contrast sensitivity function? [PDF]

, 2015
Haar, Jérémy, Kimpe, Tom, Philips, Wilfried, Piepers, Bastian, Platisa, Ljiljana, Rousson, Johanna   +5 more
core  

Differential expression of cancer‐related genes supports prediction of poor response to first‐line treatments in T‐ALL pediatric patients with high minimal residual disease

Molecular Oncology, EarlyView.
In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera, Laura Vela‐Martín, Pablo Fernández‐Navarro, José Luis López‐Lorenzo, Javier Cornago, Pilar Llamas, Eduardo Pérez‐Gómez, José Luis Marín‐Rubio, Manuel Fresno, Javier Santos, José Fernández‐Piqueras, María Villa‐Morales   +11 more
wiley   +1 more source

Reduced Macular Pigment Optical Volume Is Linked to High-Risk OCT Biomarkers and Lower Contrast Sensitivity Function in iAMD. [PDF]

Invest Ophthalmol Vis Sci
Nodecker KN, Romano F, Stettler I, Shah S, Ploumi I, Cort T, Ding X, Chen C, Zhu Y, Nigalye A, Choi H, Gumustop S, Bannerman A, Vingopoulos F, Laíns I, Miller JW, Vavvas DG, Husain D, Miller JB.   +18 more
europepmc   +1 more source

Letter to the editor concerning "Contrast sensitivity function with soft contact lens wear". [PDF]

J Optom, 2021
Erdinest N, London N.
europepmc   +1 more source

E2A selectively regulates TGF‐β–induced apoptosis in KRAS‐mutant non‐small cell lung cancer

Molecular Oncology, EarlyView.
Ability to induce apoptosis by TGF‐β is frequently lost in advanced lung adenocarcinoma despite intact TGF‐β signaling. We identify E2A as a mutant KRAS–dependent mediator of resistance to TGF‐β–induced apoptosis. TGF‐β induces E2A via SMAD3 in mutant KRAS cells, and E2A silencing restores apoptosis and enhances radiation response in cell lines ...
Sergei Chuikov, Shiva Krishna Katkam, Zhefan Wang, Venkateshwar G. Keshamouni   +3 more
wiley   +1 more source

Reply to letter to the editor by London and Erdinest on "Contrast sensitivity function with soft contact lens wear". [PDF]

J Optom, 2021
Sapkota K, Franco S, Lira M.
europepmc   +1 more source

CD47 promotes mitogen‐activated protein kinase and epithelial‐to‐mesenchymal transition molecular programs to drive prometastatic phenotypes in non‐small cell lung cancer

Molecular Oncology, EarlyView.
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau, Lilian G. Zhai, Ryunosuke Hoshi, Zackary Rousseau, Abraam Zakhary, Yin Fang Wu, Rola M. Saleeb, Heyu Ni, Kelsie L. Thu   +8 more
wiley   +1 more source