Results 91 to 100 of about 1,449,260 (305)
Calpain small subunit homodimerization is robust and calcium‐independent
FEBS Letters, EarlyView.Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source
Subphonemic and suballophonic consonant variation : the role of the phoneme inventory
, 2013 Consonants exhibit more variation in their phonetic realization than is typically acknowledged, but that variation is linguistically constrained. Acoustic analysis of both read and spontaneous speech reveals that consonants are not necessarily realized ...
Lavoie, Lisa M.
core
Imaging optical thicknesses and separation distances of phospholipid vesicles at solid surfaces [PDF]
, 1992 We present the application of reflection interference contrast microscopy (RICM) (1) to map the optical density of supported bilayers and vesicles and (2) to image the contact profile of phospholipid vesicles at surfaces.
Sackmann, E. +3 more
core +1 more source
Magnetic Nanoparticle-Guided Blind Focusing of the Electric Field for Microwave Hyperthermia
IEEE Access, 2017 This paper deals with microwave hyperthermia, presenting a novel way to achieve the blind focusing on the tumor of the electric field radiated by an array of antennas.
Gennaro Bellizzi, Ovidio Mario Bucci
doaj +1 more source
Contrastive Variational Autoencoder Enhances Salient Features
CoRR, 2019 Submitted to ICML ...
Abubakar Abid, James Y. Zou
openaire +2 more sources
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
Journal of Mathematical Sciences and ModellingParkinson’s disease (PD) is a neurodegenerative disorder that most profoundly affects motor capabilities. Machine learning approaches have emerged as potential tools for early diagnosis, accomplished through analysis of impairments exhibited in ...
Ramiz Görkem Birdal
doaj +1 more source
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
Ultrasound International Open, 2017 Purpose Dynamic contrast-enhanced ultrasound (DCE-US) can be used for calculating organ perfusion. By combining bolus injection with burst replenishment, the actual mean transit time (MTT) can be estimated.
Marcus Stangeland +6 more
doaj +1 more source
Oil seal surface defect detection using superpixel segmentation and circumferential difference
International Journal of Advanced Robotic Systems, 2020 Surface defects affect the quality and safety of oil seals. It is a challenge to detect such defects in a vision system because of the unequal reflection property of oil seal surfaces and low contrast between the defect and the background.
Zhendong He +5 more
doaj +1 more source