Results 31 to 40 of about 106,109 (302)

The margin of appreciation doctrine and the interpretation of the European Convention on Human Rights as a living instrument [PDF]

open access: yes, 2018
The significance of the margin of appreciation doctrine has been underscored recently with the adoption of Protocol No 15 which calls for the inclusion of the terms ‘margin of appreciation’ and ‘subsidiarity’ in the Preamble of the European Convention on
Ita, Rachael Eguono
core   +1 more source

Convexity and marginal contributions in bankruptcy games [PDF]

open access: yesEconoQuantum, 2011
En este trabajo analizamos dos definiciones naturales de convexidad para los juegos de bancarrota, una de ellas fue introducida por Aumann y Maschler (1985). En particular, mostramos que la convexidad, entendida como contribuciones marginales crecientes, no se satisface en el juego presentado por estos autores.
Leobardo Plata-Perez, Joss Sanchez-Perez
openaire   +4 more sources

Passive margins in accreting Archaean archipelagos signal continental stability promoting early atmospheric oxygen rise

open access: yesNature Communications, 2022
This research reports a 2.5-billion year-old passive margin formed in accreting archipelagos, highlighting the contribution of early continent formation and the relationship between continental stabilization and early atmospheric oxygen rise.
Yaying Peng   +7 more
doaj   +1 more source

ANALISIS CONTRIBUTION MARGIN DALAM KAITANNYA DENGAN PENGEMBANGAN PRODUK PADA PT. MAYANG SARI JEMBER [PDF]

open access: yes, 2014
Penelitian ini bertujuan untuk mengetahui “ Contribution Margin Dalam Kaitannya Dengan Pengembangan Produk”. Penelitian ini dilakukan pada PT. Mayang Sari Jember.
VINA ELINAWATI
core   +1 more source

Avaliação das equipes de vendas de duas empresas com a matriz BCG utilizando lucro e margem de contribuição

open access: yesGestão & Produção, 2018
Resumo No presente trabalho o método da matriz BCG foi adaptado para ser utilizado na avaliação do desempenho das equipes de vendas de duas empresas de segmentos e tamanhos diferentes, sendo uma empresa fabricante de móveis e a outra uma fabricante de ...
Roque Alberto Zin   +2 more
doaj   +1 more source

Enteropathogenic E. coli shows delayed attachment and host response in human jejunum organoid‐derived monolayers compared to HeLa cells

open access: yesFEBS Letters, EarlyView.
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi   +5 more
wiley   +1 more source

Seismic structure of the continental margin of French Guiana: implications for the rifting and early spreading of the equatorial Atlantic [PDF]

open access: yes, 2007
Recent studies of passive continental margins suggest that the rifting process produces a variety of structural styles. The along-strike continuity of these rifted margins is punctuated by significant lateral offsets, known as transform margins.
Greenroyd, Christopher J.   +1 more
core  

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

open access: yesMolecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat   +8 more
wiley   +1 more source

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

open access: yesMolecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano   +6 more
wiley   +1 more source

Neogene paleomagnetism and geodynamics of the Hikurangi margin, East Coast, New Zealand [PDF]

open access: yes, 2006
Vertical-axis rotations are an important component of Neogene deformation in the New Zealand plate boundary region, and potentially offer fundamental insights into the rheology of continental crust.
Rowan, C.J., Rowan, Christopher James
core  

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