Results 61 to 70 of about 4,163,984 (363)

In vitro properties of patient serum predict clinical outcome after high dose rate brachytherapy of hepatocellular carcinoma

Molecular Oncology, EarlyView.
Following high dose rate brachytherapy (HDR‐BT) for hepatocellular carcinoma (HCC), patients were classified as responders and nonresponders. Post‐therapy serum induced increased BrdU incorporation and Cyclin E expression of Huh7 and HepG2 cells in nonresponders, but decreased levels in responders.
Lukas Salvermoser, Jan Niklas Schäfer, Shraga Nahum Goldberg, Philipp Maximilian Kazmierczak, Moritz Nikolaus Gröper, Philipp Franz Linden, Elif Öcal, Tanja Burkard, Stefanie Corradini, Najib Ben Khaled, Moritz Wildgruber, Max Seidensticker, Jens Ricke, Matthias Stechele, Marianna Alunni‐Fabbroni   +14 more
wiley   +1 more source

Unprecedented Fe delivery from the Congo River margin to the South Atlantic Gyre

Nature Communications, 2020
Rivers are a major supplier of particulate and dissolved material to the ocean, but their role as sources of bio-essential dissolved iron (dFe) is thought to be limited due to rapid, efficient Fe removal during estuarine mixing.
Lúcia H. Vieira, Stephan Krisch, M. Hopwood, A. Beck, J. Scholten, V. Liebetrau, E. Achterberg   +6 more
semanticscholar   +1 more source

Patient‐specific pharmacogenomics demonstrates xCT as predictive therapeutic target in colon cancer with possible implications in tumor connectivity

Molecular Oncology, EarlyView.
This study integrates transcriptomic profiling of matched tumor and healthy tissues from 32 colorectal cancer patients with functional validation in patient‐derived organoids, revealing dysregulated metabolic programs driven by overexpressed xCT (SLC7A11) and SLC3A2, identifying an oncogenic cystine/glutamate transporter signature linked to ...
Marco Strecker, Keren Zohar, Martin Böttcher, Thomas Wartmann, Henry Freudenstein, Maximilian Doelling, Mihailo Andric, Wenjie Shi, Or Kakhlon, Katrin Hippe, Beatrix Jahnke, Dimitrios Mougiakakos, Franziska Baenke, Daniel Stange, Roland S. Croner, Michal Linial, Ulf D. Kahlert   +16 more
wiley   +1 more source

Detection of circulating tumor DNA in colorectal cancer patients using a methylation‐specific droplet digital PCR multiplex

Molecular Oncology, EarlyView.
We developed a cost‐effective methylation‐specific droplet digital PCR multiplex assay containing tissue‐conserved and tumor‐specific methylation markers. The assay can detect circulating tumor DNA with high accuracy in patients with localized and metastatic colorectal cancer.
Luisa Matos do Canto, Louise Raunkilde, Jan Lindebjerg, Mads Malik Aagaard, Christina Therkildsen, Jakob Kleif, Lars Henrik Jensen, Torben Frøstrup Hansen, Rikke Fredslund Andersen   +8 more
wiley   +1 more source

An Iterative Method to Derive the Equivalent Centrifugal Compressor Performance at Various Operating Conditions: Part II: Modeling of Gas Properties Impact [PDF]

, 2015
This is the second part of a study conducted to model the aerothermodynamic impact of suction parameters and gas properties on a multi-stage centrifugal compressor’s performance.
Albusaidi, Waleed, Pilidis, Pericles
core   +2 more sources

Developing evidence‐based, cost‐effective P4 cancer medicine for driving innovation in prevention, therapeutics, patient care and reducing healthcare inequalities

Molecular Oncology, EarlyView.
The cancer problem is increasing globally with projections up to the year 2050 showing unfavourable outcomes in terms of incidence and cancer‐related deaths. The main challenges are prevention, improved therapeutics resulting in increased cure rates and enhanced health‐related quality of life.
Ulrik Ringborg, Joachim von Braun, Julio Celis, Anton Berns, Michael Baumann, Tit Albreht, Nancy Abou‐Zeid, Vanderlei Bagnato, Christian Brandts, Chien‐Jen Chen, Massimiliano di Pietro, Manjit Dosanjh, Thomas Dubois, Alexander Eggermont, Angelika Eggert, Ingemar Ernberg, Sara Faithfull, Johannes Förner, Stefan Fröhling, Manuel Heitor, Leroy Hood, Wei Jiang, Bengt Jönsson, Ravi Kannan, Maria Leptin, Su Li, Peter Lindgren, Douglas Lowy, Jun Ma, Alex Markham, Péter Nagy, Simon Oberst, M. Iqbal Parker, Danielle Rodin, Kevin Ryan, Joachim Schüz, Richard Sullivan, Josep Tabernero, Peter Turkson, Oliver Várhelyi, Harold Varmus, Chijie Wang, Elisabete Weiderpass, Nils Wilking   +43 more
wiley   +1 more source

The Effect of the Uruguay round on the Intensive and Extensive Margins of Trade [PDF]

Do tariffs inhibit trade flows by limiting the entry of exporting firms (extensive margin') or by restricting the average volume exported by each firm (intensive margin')? Using a gravity equation approach, we analyze how the decrease in tariffs promoted
G. LALANNE, I. BUONO
core   +3 more sources

Análise de rentabilidade dos segmentos de mercado de empresa distribuidora de mercadorias

Revista Contabilidade & Finanças, 2004
O artigo apresenta possíveis aplicações do conceito de margem de contribuição para avaliação de desempenho de segmentos comerciais, voltando-se mais especificamente para empresas que operam no ramo de distribuição de mercadorias.
Rodney Wernke, Marluce Lembeck
doaj   +1 more source

The Strike-Slip Fault Effects on Tight Ordovician Reef-Shoal Reservoirs in the Central Tarim Basin (NW China)

Energies, 2023
The largest carbonate condensate field in China has been found in the central Tarim Basin. Ordovician carbonate reservoirs are generally attributed to reef-shoal microfacies along a platform margin.
Yawen Zhao, Guanghui Wu, Yintao Zhang, Nicola Scarselli, Wei Yan, Chong Sun, Jianfa Han   +6 more
doaj   +1 more source

Invisible contributions of marginalized genders in hydrology

, 2023
As the International Association of Hydrological Sciences History of Hydrology Working Group mission notes, there is no readily available source of information about the history of hydrology and hydrologists. In particular, the contributions of marginalized genders in hydrology have been – and continue to be – invisible, overlooked, or disregarded,
Archfield, S., Gascuel, C., Marshall, L., Cavus, Y.   +3 more
openaire   +2 more sources