Results 91 to 100 of about 6,056,553 (315)
The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes
Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga +3 more
wiley +1 more source
SALARIES AND MEDICAL CERTIFICATES. RECOGNITION IN ACCOUNTING AND TAX EFFECTS [PDF]
Salaries represent employees' monetary rights and expenses for employers. Through this article we aim to highlight the complex way of calculating wage entitlements (although at present it is conveyed by the political system that due to the single rate,
Sorin-Constantin Deaconu
doaj
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley +1 more source
Berní zatížení českého venkova v první polovině 19. století a úskalí jeho studia // The tax burden on the Czech countryside in the first half of the 19th century and some pitfalls in its studies [PDF]
The paper summarises the possibilities of studying the tax burden on the Czech countryside in 1780–1850. For its analysis it proposes to use the archival collection ‘Contribution Funds’, consisting of individual schedules for the planned contributions (
Jan Lhoták
doaj
Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil +4 more
wiley +1 more source
The Returns from Rent-Seeking: Campaign Contributions, Firm Subsidies, and the Byrd Amendment [PDF]
This paper examines Congressional support of the Byrd Amendment, a new antidumping law that directs the U.S. Customs Service to distribute collected duties to protected firms.
Benjamin Liebman, Kara M. Olson
core
pH‐mediated activation of the lysosomal arginine sensor SLC38A9
Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley +1 more source
Does Political Ambiguity Pay? Corporate Campaign Contributions and the Rewards to Legislator Reputation [PDF]
Do politicians tend to follow a strategy of ambiguity in their policy positions or a strategy of reputational development to reduce uncertainty about where they stand?
Randall S. Kroszner, Thomas Stratmann
core
Corporations and their contributions to public debates [PDF]
Corporations are increasingly seeking to engage in public debates on contentious matters of public policy. Regardless of whether or not one agrees with particular positions taken, the question arises as to whether officers of corporations that devote ...
Gray, Anthony
core

