Results 111 to 120 of about 6,056,553 (315)
This study reveals that the small GTPase Rab14 is necessary for human papillomavirus (HPV) infection and plays an essential role in the transport of virions to the trans‐Golgi network (TGN). HPV in the early endosome (EE), which harbors GTP‐bound Rab14, is transported to the TGN through the switch of Rab14 from its GTP‐bound to GDP‐bound form.
Yoshiyuki Ishii, Iwao Kukimoto
wiley +1 more source
Introduction The peer review process is essential to ensure the quality, rigor, and relevance of scientific publications. The International Journal of Innovation (IJI), a journal dedicated to disseminating research on innovation with an emphasis on ...
Fernando Antonio Ribeiro Serra +4 more
doaj +1 more source
Degradation mechanism of the von Willebrand factor A2 domain by nattokinase
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto +3 more
wiley +1 more source
Contributions from the Physical Laboratory.
Vols. for ̂̂̂in its Papers,Mode of access: Internet.Superseded by and included in its Contributions from the Physics ...
University of Michigan. Dept. of physics.
core
Contributions Agency business plan 1992/1993
SIGLEAvailable from British Library Document Supply Centre- DSC:3458.18(1992/1993) / BLDSC - British Library Document Supply CentreGBUnited ...
Contributions Agency (United Kingdom)
core
Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations
The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas +6 more
wiley +1 more source
Contributions from the Physics laboratory.
Mode of access: Internet.Supersedes and contains its Contributions from the Physical laboratory, no.
University of Michigan. Dept. of Physics.
core
The ubiquitin‐proteasome system and autophagy as guardians of the cellular proteome
This Perspective covers the three principles governing the crosstalk between the ubiquitin‐proteasome system and autophagy in cellular proteostasis: (1) a shared ubiquitin code routing substrates via shuttle factors or autophagy receptors; (2) spatial compartmentalization into phase‐separated degradation hubs and organelle‐specific modules (exemplified
Ivan Dikic
wiley +1 more source
Contributions Agency business plan 1991/92
SIGLEAvailable from British Library Document Supply Centre- DSC:3458.18(1991/1992) / BLDSC - British Library Document Supply CentreGBUnited ...
Contributions Agency (United Kingdom)
core
An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley +1 more source

