Results 111 to 120 of about 6,056,553 (315)

Rab14 regulates the transport of human papillomavirus to the trans‐Golgi network for infectious cell entry

open access: yesFEBS Letters, EarlyView.
This study reveals that the small GTPase Rab14 is necessary for human papillomavirus (HPV) infection and plays an essential role in the transport of virions to the trans‐Golgi network (TGN). HPV in the early endosome (EE), which harbors GTP‐bound Rab14, is transported to the TGN through the switch of Rab14 from its GTP‐bound to GDP‐bound form.
Yoshiyuki Ishii, Iwao Kukimoto
wiley   +1 more source

The importance of the reviewer's role in the development of innovation research: Guidelines for constructive contributions

open access: yesInternational Journal of Innovation
Introduction The peer review process is essential to ensure the quality, rigor, and relevance of scientific publications. The International Journal of Innovation (IJI), a journal dedicated to disseminating research on innovation with an emphasis on ...
Fernando Antonio Ribeiro Serra   +4 more
doaj   +1 more source

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

open access: yesFEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto   +3 more
wiley   +1 more source

Contributions from the Physical Laboratory.

open access: yes
Vols. for ̂̂̂in its Papers,Mode of access: Internet.Superseded by and included in its Contributions from the Physics ...
University of Michigan. Dept. of physics.
core  

Contributions Agency business plan 1992/1993

open access: yes, 1992
SIGLEAvailable from British Library Document Supply Centre- DSC:3458.18(1992/1993) / BLDSC - British Library Document Supply CentreGBUnited ...
Contributions Agency (United Kingdom)
core  

Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations

open access: yesFEBS Letters, EarlyView.
The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas   +6 more
wiley   +1 more source

Contributions from the Physics laboratory.

open access: yes
Mode of access: Internet.Supersedes and contains its Contributions from the Physical laboratory, no.
University of Michigan. Dept. of Physics.
core  

The ubiquitin‐proteasome system and autophagy as guardians of the cellular proteome

open access: yesFEBS Letters, EarlyView.
This Perspective covers the three principles governing the crosstalk between the ubiquitin‐proteasome system and autophagy in cellular proteostasis: (1) a shared ubiquitin code routing substrates via shuttle factors or autophagy receptors; (2) spatial compartmentalization into phase‐separated degradation hubs and organelle‐specific modules (exemplified
Ivan Dikic
wiley   +1 more source

Contributions Agency business plan 1991/92

open access: yes, 1992
SIGLEAvailable from British Library Document Supply Centre- DSC:3458.18(1991/1992) / BLDSC - British Library Document Supply CentreGBUnited ...
Contributions Agency (United Kingdom)
core  

An unexpected alternative viologen electron mediator site in tungsten‐containing formate dehydrogenase

open access: yesFEBS Letters, EarlyView.
An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley   +1 more source

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