Results 81 to 90 of about 28,598,086 (367)
Decoding the dual role of autophagy in cancer through transcriptional and epigenetic regulation
FEBS Letters, EarlyView.Transcriptional and epigenetic regulation controls autophagy, which exerts context‐dependent effects on cancer: Autophagy suppresses tumorigenesis by maintaining cellular homeostasis or promotes tumor progression by supporting survival under stress. In this “In a Nutshell” article, we explore the intricate mechanisms of the dual function of autophagy ...
Young Suk Yu, Ik Soo Kim, Sung Hee Baek
wiley +1 more source
Autophagy in cancer and protein conformational disorders
FEBS Letters, EarlyView.Autophagy plays a crucial role in numerous biological processes, including protein and organelle quality control, development, immunity, and metabolism. Hence, dysregulation or mutations in autophagy‐related genes have been implicated in a wide range of human diseases.
Sergio Attanasio
wiley +1 more source
500 Cities Project: Local Data for Better Health 2014 [PDF]
, 2016 The 500 Cities Project-Local Data for Better Health-is a collaboration among the Robert Wood Johnson Foundation, the CDC Foundation, and the Centers for Disease Control and Prevention (CDC), whose purpose is to provide high quality small area estimates ...
Center for Disease Control and Prevention +1 more
core +1 more source
Model predictive control of a variable-speed pitch-regulated wind turbine [PDF]
, 2016 The Model Predictive Controller is designed for a 5MW variable-speed pitch-regulated wind turbine for three operating points – below rated wind speed, just above rated wind speed, and above rated wind speed.
Hur, Sung Ho, Leithead, William
core +1 more source
A stepwise emergence of evolution in the RNA world
FEBS Letters, EarlyView.How did biological evolution emerge from chemical reactions? This perspective proposes a gradual scenario of self‐organization among RNA molecules, where catalytic feedback on random mixtures plays the central role. Short oligomers cross‐ligate, and self‐assembly enables heritable variations. An event of template‐externalization marks the transition to
Philippe Nghe
wiley +1 more source
Modified Pro-Self Pain Control to Increase Activity in Patients with Colorectal Cancer [PDF]
, 2017 Background: Barriers to performing activities of daily living are common complaints of patients with cancer. One of the factors causing these barriers is pain.
Mardiyono, M. (Mardiyono) +2 more
core +1 more source
FEBS Letters, EarlyView.The enzyme 5‐lipoxygenase (5‐LOX) catalyzes the first step in the biosynthesis of leukotrienes (LTs) involved in inflammatory pathophysiology. After cellular stimulation, 5‐LOX translocates to the nucleus, interacting with the 5‐LOX‐activating protein (FLAP) to form LTA4 from arachidonic acid (AA).
Erik Romp +5 more
wiley +1 more source
Reinforcement Learning for Traffic Control with Adaptive Horizon [PDF]
arXiv, 2019 This paper proposes a reinforcement learning approach for traffic control with the adaptive horizon. To build the controller for the traffic network, a Q-learning-based strategy that controls the green light passing time at the network intersections is applied.
arxiv
Brucella NyxA and NyxB dimerization enhances effector function during infection
FEBS Letters, EarlyView.Brucella abortus thrives inside cells thanks to the translocation of effector proteins that fine‐tune cellular functions. NyxA and NyxB are two effectors that destabilize the nucleolar localization of their host target, SENP3. We show that the Nyx proteins directly interact with each other and that their dimerization is essential for their function ...
Lison Cancade‐Veyre +4 more
wiley +1 more source
Control of control charts [PDF]
, 2005 Although the Shewhart chart is widely used in practice because of its simplicity, applying this control chart to monitor the mean of a process may lead to two types of problems.
Nurdiati, Sri
core +4 more sources