Results 101 to 110 of about 1,118,651 (312)
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane +11 more
wiley +1 more source
RoundMi: A quantitative method to analyze mitochondrial morphology in mitotic cells
RoundMi is a workflow for rapid analysis of mitochondrial morphology in mitotic cells. By combining adaptive preprocessing with automated segmentation and quantification, it enables accurate measurements from single focal plane images, reducing acquisition time and computational demands while remaining compatible with high‐throughput fixed and live ...
Elmira Parvindokht Bararpour +2 more
wiley +1 more source
Novel multi-rate multicast congestion control algorithm
A novel congestion control mechanism based on packet-bunch probe and TCP throughput formula(PTMCC) was proposed.This receiver-driven multi-rate multicast congestion control mechanism probes available bandwidth by packet-bunch and gets TCP-friendly rate ...
ZHANG Deng-yin +3 more
doaj +2 more sources
Molecular characterization of covRS mutations in M1UK Streptococcus pyogenes
Group A Streptococcus (GAS) acquires covRS mutations driving a hypervirulent bacterial state, frequently associated with invasive disease‐like necrotizing fasciitis. We demonstrate that the newly emerged M1UK GAS lineage can also acquire these mutations.
Jarrad Pritchard +12 more
wiley +1 more source
Transcripts enriched in codons that trigger P‐site tRNA‐mediated mRNA decay possess stable mRNA
PTMD codons were first described by Mendel et al. as mediators of an mRNA decay pathway dependent on the human protein CNOT3, homologous to yeast Not5. Our findings confirm that PTMD codons destabilize transcripts; however, unlike in yeast, the human pathway specifically targets and slightly destabilizes primarily stable mRNAs.
Rodolfo Lopes Carneiro +1 more
wiley +1 more source
Proposing an Algorithm for R&Q Inventory Control Model with Stochastic Demand Influenced by Shortage
In this article, the continuous - review inventory control system has been studied. A new constraint of demand dependent on the average percent of product shortage has been added to the problem.
Parviz fattahi +3 more
doaj
Multiobjective PI/PID Control Design Using an Iterative Linear Matrix Inequalities Algorithm
Many real world control systems usually track several control objectives,simultaneously. At the moment, it is desirable to meet all specified goals using the controllers\ud with simple structures like as proportional-integral (PI) and proportional ...
Bevrani, Hassan, Hiyama, Takashi
core
A Formulation of nonlinear model predictive control using automatic differentiation [PDF]
An efficient algorithm is developed to alleviate the computational burden associated with nonlinear model predictive control (NMPC). The new algorithm extends an existing algorithm for solutions of dynamic sensitivity from autonomous to non-autonomous ...
Cao, Yi
core +1 more source
Intelligent Tutoring Systems for Adult Learning in STEM Disciplines
ABSTRACT Intelligent tutoring systems (ITS) are reshaping adult learning in STEM by providing adaptive, data‐driven instruction across classrooms, workplaces, and informal environments. In the context of ITS, this article compares generative AI, which creates personalized explanations and practice materials, with explainable AI, which focuses on ...
Jill Zarestky, Amanda R. Lager Gleason
wiley +1 more source
The Pitch Control Algorithm of Wind Turbine Based on Fuzzy Control and PID Control
Due to the special features of great inertia, pure lag and non-linearity provided with wind turbine, coupled with complex and variable working condition, it is difficult to achieve satisfactory control results simply by employing traditional PID, which ...
Liu YY(刘意杨) +3 more
core

