Results 81 to 90 of about 1,118,651 (312)

Liquid biopsy‐based diagnostic evaluation of hypermethylated CpG sites for ovarian cancer diagnosis

Molecular Oncology, EarlyView.
This schematic outlines the workflow from biomarker identification to duplex MethyLight assay validation for epithelial ovarian cancer diagnosis using cfDNA‐based liquid biopsy. Initial screening of hypermethylated CpG candidates (cg02957270, cg10061138 cg00480298, COL2A1) was performed in tissue using ARMS‐PCR, COBRA, qPCR and image analysis. Selected
Deepa Bisht, Sameer Gupta, Amrita Chaurasia, Manisha Sachan   +3 more
wiley   +1 more source

Ant colony algorithm and fuzzy neural network-based intelligent dispatching algorithm of an elevator group control system

, 2007
To improve the performance of elevator group control systems (EGCS), an intelligent dispatching method based on ant colony algorithm and fuzzy neural network is presented.
刘意杨, Liu, Jianchang
core  

Practical application of active noise control in a duct using predictive control [PDF]

, 2002
This paper presents a practical application of Active Noise Control (ANC) using the Generalised Predictive Control (GPC) algorithm. The main objective of this application was to reduce significantly the noise level in a duct using this technique.
Nistor, Ionel, Bordeneuve-Guibé, Joël
core  

Patient therapy outcome modeling in cancer organoids is improved by cancer‐associated fibroblasts and organoid assembly convolution

Molecular Oncology, EarlyView.
Patient‐derived organoids (PDOs) from pancreatic, colorectal, and gastric cancers were used to evaluate standard and experimental therapies. Incorporating cancer‐associated fibroblasts (CAFs) into organoid cultures improved patient therapy outcome prediction.
Marcin Grochowski, Liudmyla Dolinchuk, Michał Jerzak, Albert Gandurski, Tomasz Grochowski, Weronika Wojtyś, Maciej Zadrożny, Wojciech Kaźmierczak, Małgorzata Lenarcik, Marta Matejak‐Górska, Radosław Samsel, Tomasz Olesiński, Dawid Walerych   +12 more
wiley   +1 more source

Leader-Following Diffusion-Based Reactive Power Coordination and Voltage Control of Offshore Wind Farm

IEEE Access, 2020
This paper proposed a distributed reactive power coordination and voltage control of offshore wind farm based on the leader-following diffusion algorithm.
Thai-Thanh Nguyen, Hak-Man Kim
doaj   +1 more source

An algorithm for weak synthesis observation equivalence for compositional supervisor synthesis

, 2012
This paper proposes an algorithm to simplify automata in such a way that compositional synthesis results are preserved in every possible context. It relaxes some requirements of synthesis observation equivalence from previous work, so that better ...
Fabian, Martin,, Mohajerani, Sahar, Malik, Robi, Mohajerani, Sahar,, Fabian, Martin   +4 more
core   +1 more source

Epigenetic heterogeneity and plasticity in therapy‐induced tumor states through single‐cell multi‐omics

Molecular Oncology, EarlyView.
Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim, Hwiyeong Lee, Jin Hong, Daechan Park   +3 more
wiley   +1 more source

PAK1 activation drives divergent resistance mechanisms to aromatase inhibition and tamoxifen in a luminal: A breast cancer model

Molecular Oncology, EarlyView.
Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller, Janina Müller, Efstathios‐Iason Vlachavas, Lukas Beumers, Lena Fleischhacker, Sara Burmester, Angelika Wörner, Sabine Karolus, Dominic Helm, Cindy Körner, Stefan Wiemann   +10 more
wiley   +1 more source

A method of adaptation between steepest-descent and Newton's algorithm for multichannel active control of tonal noise and vibration

, 2014
Active control methods have been applied to a number of practical problems in which it is necessary to control a tonal disturbance. For example, the control of engine noise and vibration in vehicles, propeller noise in aircraft and the vibration produced
Cheer, Jordan, Daley, Stephen
core  

ZW4864‐mediated inhibition of the β‐catenin/BCL9/BCL9L complex reveals therapeutic potential in bladder cancer

Molecular Oncology, EarlyView.
BCL9 and BCL9L drive bladder cancer progression by enhancing β‐catenin signaling, promoting proliferation, migration, invasion, and organoid growth. Genetic depletion of BCL9(L) suppresses malignant phenotypes, while pharmacological disruption of the β‐catenin/BCL9(L) complex with ZW4864 inhibits canonical Wnt signaling and tumor‐associated cellular ...
Roland Kotolloshi, Mandy Berndt‐Paetz, Eileen Lerner, Gregoire Najjar, Anca Azoitei, Krishna Pal Singh, Shailendra Kumar Gupta, Olaf Wolkenhauer, Cagatay Günes, Otmar Huber, Marc‐Oliver Grimm, Daniel Steinbach   +11 more
wiley   +1 more source