Results 61 to 70 of about 1,118,651 (312)

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch, Isabel Vogel, Sina Nokodian, Johanna Moeller, Antonia Blechschmidt, Vicky Hecht, Vanessa Kuentzel, Katharina Thiedig, Melissa Schwab, Oliver Schilling, Holger Bronger, Marion Kiechle, Viktor Magdolen, Tobias Dreyer   +13 more
wiley   +1 more source

Classification of Canal Control Algorithms [PDF]

Journal of Irrigation and Drainage Engineering, 1998
Different control algorithms for the regulation of irrigation canals have been developed and applied throughout the world. Each of them can be characterized according to several criteria, among which are: the considered variables (controlled, measured, and control action variables), the logic of control (type and direction), and the design technique ...
Malaterre, P.O., Rogers, D.C., Schuurmans, J.   +2 more
openaire   +3 more sources

Battery - Ultracapacitor Energy Storage System Set Up Control through Fuzzy Logic Algorithm [PDF]

, 2023
The aim of this work is to show the impact of an Energy Storage System (ESS) management on the energy transfer processes during load variations.
Moualek, R., Bousbaine, A., Benamrouche, N.   +2 more
core  

Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma

Molecular Oncology, EarlyView.
The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic, Anne Nørremølle, Lilian Bomme Ousager, Lars van Brakel Andersen, Marie Louise Mølgaard Binderup, Mads Thomassen   +5 more
wiley   +1 more source

Improved ABR flow control algorithm

Tongxin xuebao, 2005
To improve the performance of traffic management of ATM networks, an improved ABR flow control algorithm was proposed based on discrete model. The effect of the delay elements was considered further with the structure of follow-up control system.
LIU Zhi-xin, GUAN Xin-ping, LONG Cheng-nian   +2 more
doaj   +2 more sources

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

Molecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova, Michele Montrone, Uday Rangaswamy, Francesco Diversi, Irene Schiavo, Denise Ferrarini, Roberta Di Florio, Irene Longo, Michele Coscia, Nicola Zamboni, Giorgia Demontis, Lisa Veghini, Vincenzo Corbo, Remo Sanges, Paul Heppenstall   +14 more
wiley   +1 more source

Crossroad control algorithm based on V2I-interaction

Системный анализ и прикладная информатика, 2019
The importance of efficient traffic management problem grows every year. Constantly increasing number of vehicles and traffic volume requires improvement of methods and algorithms of traffic control. Such improvement becomes possible due to the spreading
A. N. Klimovich, V. N. Shuts
doaj   +1 more source

Inferential control with the aid of modified QPLS-based soft sensor for an industrial FCCU fractionator [PDF]

, 2010
A modified quadratic partial least squares (MQPLS) algorithm based on non-linear constrained programming is proposed, in which a sequential unconstrained minimisation technique is employed to calculate the outer input weights and the parameters of inner ...
Yang, Minghui, Sheng Chen, Tu, Ling, Xuemin Tian, Chen, Sheng, Ling Tu, Tian, Xuemin, Minghui Yang   +7 more
core   +1 more source

Heterozygous loss‐of‐function alleles associate the conserved 3′‐5′ exoribonuclease EXOSC10 with hypersensitivity to the anticancer drug 5‐fluorouracil

Molecular Oncology, EarlyView.
EXOSC10, an essential nuclear RNA exosome‐associated 3′‐5′ exoribonuclease, is inhibited by the anticancer drug 5‐fluorouracil (5‐FU), and EXOSC10 depletion increases 5‐FU sensitivity. The colon‐cancer variant EXOSC10S402T, located in a proteolysis motif, is stable and nuclear but nonfunctional in vivo.
Radhika Sain, Yann Le Page, Frédéric Percevault, Emmanuelle Becker, Luc Negroni, Almudena Fernandez, Marta Cantero, Diego Muñoz‐Santos, Lluís Montoliu, Cyrille Garnier, Michael Primig   +10 more
wiley   +1 more source

Adaptor protein CIN85 potentiates the motility of osteosarcoma cells via the Akt/mTOR and MMP2‐COL3A1 axis

Molecular Oncology, EarlyView.
CIN85 is highly expressed in osteosarcoma, particularly in metastatic lesions. Its overexpression increases cell migration and Matrigel invasion, while silencing CIN85 suppresses these behaviors. Transcriptome analysis shows that CIN85 regulates MMP2, COL3A1, and Akt/mTOR signaling. Targeting these pathways reverses CIN85‐induced motility, highlighting
Iryna Horak, Iva Staniczková Zambo, Matěj Přikryl, Peter Múdry, Danica Zapletalová, Jarmila Navrátilová, Jiří Navrátil, Jan Šmarda, Liudmyla Drobot, Petr Beneš, Lucia Knopfová   +10 more
wiley   +1 more source