Results 191 to 200 of about 1,613,291 (363)

Minimum size control for binary topology optimization

open access: yes
Topology optimization methods employing binary (also known as discrete) design variables currently lack mathematical formulations to ensure length scale control in their solutions.
Cortez, Rômulo L.   +3 more
core   +1 more source

RoundMi: A quantitative method to analyze mitochondrial morphology in mitotic cells

open access: yesFEBS Open Bio, EarlyView.
RoundMi is a workflow for rapid analysis of mitochondrial morphology in mitotic cells. By combining adaptive preprocessing with automated segmentation and quantification, it enables accurate measurements from single focal plane images, reducing acquisition time and computational demands while remaining compatible with high‐throughput fixed and live ...
Elmira Parvindokht Bararpour   +2 more
wiley   +1 more source

Receding Horizon Optimization Enhanced Robust GPMN Control for A Certain Kind of Nonlinear Systems

open access: yes, 2009
In this paper, a new robust and optimization based nonlinear controller with respect to a certain kind of nonlinear disturbed systems is proposed based on control Lyapunov functions (CLF) concept and receding horizon control (RHC) scheme.
He YQ(何玉庆), Han JD(韩建达)
core  

One size does not fit all: An in vitro evaluation of the effects of bezafibrate and medroxyprogesterone acetate on human SH‐SY5Y and U‐87 MG cancer cells

open access: yesFEBS Open Bio, EarlyView.
Drugs previously repurposed to target blood cancers reduced neuroblastoma and glioblastoma cell growth and viability. However, their levels of anticancer activity were different and their clinical application may be problematic due to side effects at effective doses.
Abhishek Kharawatkar   +4 more
wiley   +1 more source

Least-cost control strategy optimization for air quality attainment of Beijing-Tianjin-Hebei region in China. [PDF]

open access: yesJ Environ Manage, 2019
Xing J   +7 more
europepmc   +1 more source

Aquaporin‐3 and aquaporin‐5 impact the development of pancreatic ductal adenocarcinoma spheroids

open access: yesFEBS Open Bio, EarlyView.
Schematic representation of the role of aquaporin‐3 (AQP3) and aquaporin‐5 (AQP5) in pancreatic ductal adenocarcinoma (PDAC). Both proteins are upregulated in PDAC and are associated with tumor progression and metastatic potential. Silencing AQP3 or AQP5 in PDAC spheroids results in decreased diameter, area, and overall growth, underscoring their key ...
Catarina Pimpão   +3 more
wiley   +1 more source

Well-posedness and scalarization in vector optimization [PDF]

open access: yes
In this paper we study several existing notions of well-posedness for vector optimization problems. We distinguish them into two classes and we establish the hierarchical structure of their relationships.
Rocca Matteo   +2 more
core  

Directed evolution of enzymes at the crossroads of tradition and innovation

open access: yesFEBS Open Bio, EarlyView.
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova   +2 more
wiley   +1 more source

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