Minimum size control for binary topology optimization
Topology optimization methods employing binary (also known as discrete) design variables currently lack mathematical formulations to ensure length scale control in their solutions.
Cortez, Rômulo L. +3 more
core +1 more source
RoundMi: A quantitative method to analyze mitochondrial morphology in mitotic cells
RoundMi is a workflow for rapid analysis of mitochondrial morphology in mitotic cells. By combining adaptive preprocessing with automated segmentation and quantification, it enables accurate measurements from single focal plane images, reducing acquisition time and computational demands while remaining compatible with high‐throughput fixed and live ...
Elmira Parvindokht Bararpour +2 more
wiley +1 more source
Receding Horizon Optimization Enhanced Robust GPMN Control for A Certain Kind of Nonlinear Systems
In this paper, a new robust and optimization based nonlinear controller with respect to a certain kind of nonlinear disturbed systems is proposed based on control Lyapunov functions (CLF) concept and receding horizon control (RHC) scheme.
He YQ(何玉庆), Han JD(韩建达)
core
Drugs previously repurposed to target blood cancers reduced neuroblastoma and glioblastoma cell growth and viability. However, their levels of anticancer activity were different and their clinical application may be problematic due to side effects at effective doses.
Abhishek Kharawatkar +4 more
wiley +1 more source
Control and optimization of a half-car active suspension system with classical and modified PID-based controllers using metaheuristic techniques. [PDF]
Aysal FE +5 more
europepmc +1 more source
Least-cost control strategy optimization for air quality attainment of Beijing-Tianjin-Hebei region in China. [PDF]
Xing J +7 more
europepmc +1 more source
Aquaporin‐3 and aquaporin‐5 impact the development of pancreatic ductal adenocarcinoma spheroids
Schematic representation of the role of aquaporin‐3 (AQP3) and aquaporin‐5 (AQP5) in pancreatic ductal adenocarcinoma (PDAC). Both proteins are upregulated in PDAC and are associated with tumor progression and metastatic potential. Silencing AQP3 or AQP5 in PDAC spheroids results in decreased diameter, area, and overall growth, underscoring their key ...
Catarina Pimpão +3 more
wiley +1 more source
Oil-Water Biphasic Metal-Organic Supramolecular Gel for Lost Circulation Control: Formulation Optimization, Gelation Mechanism, and Plugging Performance. [PDF]
Li Q +7 more
europepmc +1 more source
Well-posedness and scalarization in vector optimization [PDF]
In this paper we study several existing notions of well-posedness for vector optimization problems. We distinguish them into two classes and we establish the hierarchical structure of their relationships.
Rocca Matteo +2 more
core
Directed evolution of enzymes at the crossroads of tradition and innovation
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova +2 more
wiley +1 more source

