Results 31 to 40 of about 691,986 (263)
Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?
FEBS Letters, EarlyView.This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes +3 more
wiley +1 more source
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
FEBS Letters, EarlyView.Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
IEEE Access, 2019 This paper aims to find the best variant of Cuckoo Search Algorithm that makes the step size of Lévy flight adaptive. For this reason, we introduce a new variant of CSA called Damped Cuckoo Search (DCS) in which the step size of Lévy ...
Mohamed Reda +3 more
doaj +1 more source
FEBS Letters, EarlyView.We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee +3 more
wiley +1 more source
FEBS Letters, EarlyView.We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley +1 more source
Design of Integral Sliding Mode Controller for Servo DC Motor
مجلة النهرين للعلوم الهندسية, 2017 DC servo motor is simple in construction and control and has many applications. However, the uncertainties due to its parameters changes such as load torque and friction are an evitable.
Bashar Fateh Midhat +2 more
doaj
Hand-like autonomous flying robot for airborne grasping and interaction
Nature CommunicationsBirds’ extraordinary aerial agility and environmental interaction enable complex tasks such as mid-air hunting, perching, and nest-building, inspiring the development of advanced aerial robots with similar manipulation capabilities.
Yuze Wu +6 more
doaj +1 more source
FEBS Letters, EarlyView.Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source
Diversity and complexity in neural organoids
FEBS Letters, EarlyView.Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley +1 more source
Accurate surgery time prediction (ASTP) strategy based on artificial intelligence techniques
Scientific ReportsAccurate timing prediction of surgery is essential for efficient operating room scheduling and ensuring patient care. This study proposes a two-layered Accurate Surgical Time Prediction (ASTP) framework.
Rana Mohamed El-Balka +3 more
doaj +1 more source