Results 31 to 40 of about 505,675 (253)

MITF maintains genome stability in nonmelanocyte lineages

open access: yesMolecular Oncology, EarlyView.
MITF is essential for melanocyte survival and acts as an oncogene in 10%–20% of melanomas. We show that MITF depletion causes genome instability in nonmelanocytic cells, leading to LATS2‐mediated P53 activation, cell cycle arrest, and apoptosis. This study highlights the role of MITF as a genome maintenance factor beyond the melanocyte lineage. Created
Drifa H. Gudmundsdottir   +13 more
wiley   +1 more source

GRAFIK PENGENDALI NON PARAMETRIK EMPIRIK

open access: yesMedia Statistika, 2008
Shewhart control chart is constructed base on the normality assumption of process.  If the normality is fail then the empirical control chart can be an alternative solution.
Rukun Santoso
doaj   +1 more source

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

open access: yesMolecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka   +9 more
wiley   +1 more source

New modified exponentially weighted moving average-moving average control chart for process monitoring

open access: yesConnection Science, 2022
The mixed control chart is proposed to improve detection performance with fewer process shifts. In this study, we proposed the modified exponentially weighted moving average - moving average control chart (MMEM), a new mixed control chart for observing ...
Khanittha Talordphop   +2 more
doaj   +1 more source

Preoperative circulating tumor cells integrated with imaging analysis for prognostic evaluation in head and neck squamous cell carcinoma

open access: yesMolecular Oncology, EarlyView.
Detecting circulating tumor cells (CTCs) in blood before surgery may help predict outcomes in patients with head and neck squamous cell carcinoma (HNSCC). Here, we show when combined with tumor size and lymph node involvement from routine imaging, CTC status identifies high‐risk patients with poorer survival—offering a simple, minimally invasive tool ...
Susanne Flach   +9 more
wiley   +1 more source

Analisis Kecacatan Flakes pada Produk Oriflakes di PT Serealia Prima Nutrisia Daerah Istimewa Yogyakarta

open access: yesJurnal Teknologi dan Industri Pertanian Indonesia
Product defects are one of the critical parameters to maintaining quality and consumer interest in marketed products. This study aims to determine the proportion of defects, types, and factors causing defects in flakes in Oriflakes products at PT Serelia
Farah Mustika Ningtyas   +1 more
doaj   +1 more source

Design of a Control Chart Based on COM-Poisson Distribution for the Uncertainty Environment

open access: yesComplexity, 2019
This paper will introduce the neutrosophic COM-Poisson (NCOM-Poisson) distribution. Then, the design of the attribute control chart using the NCOM-Poisson distribution is given.
Muhammad Aslam, Ali Hussein Al-Marshadi
doaj   +1 more source

Interferon beta drives therapy resistance in a patient‐derived model of high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Interferon type 1 (IFN‐1) production and signaling is associated with the acquisition of therapy resistance, following chronic DNA damage, via Interferon‐related DNA damage resistance signature (IRDS) gene expression. An alternative, DNA damage‐independent role of sustained IFN‐1 mediated resistance was identified and characterized by the emergence of ...
Ashlyn Conant   +11 more
wiley   +1 more source

SIMULATION STUDIES PERFORMANCE OF EWMA-MAX MCHART BASED ON SYNTHETIC DATA

open access: yesBarekeng
Quality control has an important role in the manufacturing process. One of the statistical tools used in quality control is Statistical Process Control (SPC). The SPC product is a control chart.
Kevin Agung Fernanda Rifki   +2 more
doaj   +1 more source

Intrapatient tumour heterogeneity and clonal evolution in an autopsy study of metastatic salivary gland cancer

open access: yesMolecular Oncology, EarlyView.
Tumour heterogeneity and clonal evolution of metastatic salivary gland cancer were evaluated in two patients with adenoid carcinoma and one patient with myoepithelial carcinoma. Radiology‐guided autopsy enabled multi‐region sampling (total samples n = 149), followed by whole‐genome sequencing and phylogenetic reconstruction (17 tumour samples, 4–7 per ...
Gerben Lassche   +10 more
wiley   +1 more source

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