Results 31 to 40 of about 505,675 (253)
MITF maintains genome stability in nonmelanocyte lineages
MITF is essential for melanocyte survival and acts as an oncogene in 10%–20% of melanomas. We show that MITF depletion causes genome instability in nonmelanocytic cells, leading to LATS2‐mediated P53 activation, cell cycle arrest, and apoptosis. This study highlights the role of MITF as a genome maintenance factor beyond the melanocyte lineage. Created
Drifa H. Gudmundsdottir +13 more
wiley +1 more source
GRAFIK PENGENDALI NON PARAMETRIK EMPIRIK
Shewhart control chart is constructed base on the normality assumption of process. If the normality is fail then the empirical control chart can be an alternative solution.
Rukun Santoso
doaj +1 more source
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka +9 more
wiley +1 more source
The mixed control chart is proposed to improve detection performance with fewer process shifts. In this study, we proposed the modified exponentially weighted moving average - moving average control chart (MMEM), a new mixed control chart for observing ...
Khanittha Talordphop +2 more
doaj +1 more source
Detecting circulating tumor cells (CTCs) in blood before surgery may help predict outcomes in patients with head and neck squamous cell carcinoma (HNSCC). Here, we show when combined with tumor size and lymph node involvement from routine imaging, CTC status identifies high‐risk patients with poorer survival—offering a simple, minimally invasive tool ...
Susanne Flach +9 more
wiley +1 more source
Product defects are one of the critical parameters to maintaining quality and consumer interest in marketed products. This study aims to determine the proportion of defects, types, and factors causing defects in flakes in Oriflakes products at PT Serelia
Farah Mustika Ningtyas +1 more
doaj +1 more source
Design of a Control Chart Based on COM-Poisson Distribution for the Uncertainty Environment
This paper will introduce the neutrosophic COM-Poisson (NCOM-Poisson) distribution. Then, the design of the attribute control chart using the NCOM-Poisson distribution is given.
Muhammad Aslam, Ali Hussein Al-Marshadi
doaj +1 more source
Interferon type 1 (IFN‐1) production and signaling is associated with the acquisition of therapy resistance, following chronic DNA damage, via Interferon‐related DNA damage resistance signature (IRDS) gene expression. An alternative, DNA damage‐independent role of sustained IFN‐1 mediated resistance was identified and characterized by the emergence of ...
Ashlyn Conant +11 more
wiley +1 more source
SIMULATION STUDIES PERFORMANCE OF EWMA-MAX MCHART BASED ON SYNTHETIC DATA
Quality control has an important role in the manufacturing process. One of the statistical tools used in quality control is Statistical Process Control (SPC). The SPC product is a control chart.
Kevin Agung Fernanda Rifki +2 more
doaj +1 more source
Tumour heterogeneity and clonal evolution of metastatic salivary gland cancer were evaluated in two patients with adenoid carcinoma and one patient with myoepithelial carcinoma. Radiology‐guided autopsy enabled multi‐region sampling (total samples n = 149), followed by whole‐genome sequencing and phylogenetic reconstruction (17 tumour samples, 4–7 per ...
Gerben Lassche +10 more
wiley +1 more source

