Results 31 to 40 of about 760,710 (275)

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

open access: yesMolecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice   +16 more
wiley   +1 more source

Control Charts for Multivariate Nonlinear Time Series

open access: yesRevstat Statistical Journal, 2015
In this paper control charts for the simultaneous monitoring of the means and the variances of multivariate nonlinear time series are introduced. The underlying target process is assumed to be a constant conditional correlation process (cf. [3]).
Robert Garthoff   +2 more
doaj   +1 more source

Estimation in Shewhart control charts [PDF]

open access: yes, 2000
The influence of the estimation of parameters in Shewhart control charts is investigated. It is shown by simulation and asymptotics that (very) large sample sizes are needed to accurately determine control charts if estimators are plugged in.
Albers, W., Kallenberg, W.C.M.
core   +1 more source

Phenotypic and genotypic characterization of single circulating tumor cells in the follow‐up of high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon   +9 more
wiley   +1 more source

On the Effect of Estimation Error for the Risk-Adjusted Charts

open access: yesComplexity, 2020
Control charts are a popular statistical process control (SPC) technique for monitoring to detect the unusual variations in different processes. Contrary to the classical charts, control charts have also been modified to include covariates using ...
Sajid Ali   +4 more
doaj   +1 more source

Exceedance probabilities for parametric control charts [PDF]

open access: yes, 2002
Common control charts assume normality and known parameters. Quite often these assumptions are not valid and large relative errors result in the usual performance characteristics, such as the false alarm rate or the average run length.
Albers, W.   +2 more
core   +1 more source

Pre‐analytical optimization of cell‐free DNA and extracellular vesicle‐derived DNA for mutation detection in liquid biopsies

open access: yesMolecular Oncology, EarlyView.
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen   +11 more
wiley   +1 more source

QUALITY OF SUGARCANE MECHANIZED PLANTING [PDF]

open access: yesEngenharia Agrícola, 2016
: The quality of the sugarcane plantation affects the plantation longevity, yield and production costs. Therefore, this study aimed to evaluate the quality of sugarcane mechanized planting in day and night shifts.
JORGE W. CORTEZ   +4 more
doaj   +1 more source

Insights into a long life without cancer: The case of the bowhead whale

open access: yesMolecular Oncology, EarlyView.
Long‐lived, large‐bodied organisms have evolved powerful anticancer mechanisms that preserve cellular and tissue integrity across extended lifespans. A recent study by Firsanov et al. shows that greater genome stability is a key factor underlying the remarkable longevity and cancer resistance of one such species, the bowhead whale.
Inés Paniagua, Johanna A. Joyce
wiley   +1 more source

Risk-Adjusted Control Charts for Health Care Monitoring

open access: yesInternational Journal of Mathematics and Mathematical Sciences, 2011
Attribute data from high-quality processes can be monitored effectively by deciding on whether or not to stop at each time where 𝑟≥1 failures have occurred.
Willem Albers
doaj   +1 more source

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