Results 121 to 130 of about 10,114,143 (309)

Mechanisms of parasite‐mediated disruption of brain vessels

FEBS Letters, EarlyView.
Parasites can affect the blood vessels of the brain, often causing serious neurological problems. This review explains how different parasites interact with and disrupt these vessels, what this means for brain health, and why these processes matter. Understanding these mechanisms may help us develop better ways to prevent or treat brain infections in ...
Leonor Loira, Sílvia Arroz‐Madeira, Cláudio A. Franco, Sara Silva Pereira   +3 more
wiley   +1 more source

Active control transport design criteria [PDF]

Vehicle design considerations for active control applications to subsonic transports are examined. Active control is defined along with those functions which are considered in the study of design criteria. The FAA regulations governing transport aircraft
Hall, B. M., Harris, R. B.
core   +1 more source

Time after time – circadian clocks through the lens of oscillator theory

FEBS Letters, EarlyView.
Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo, Carolin Ector, Hanspeter Herzel   +2 more
wiley   +1 more source

Multiple ETS family transcription factors bind mutant p53 via distinct interaction regions

FEBS Letters, EarlyView.
Mutant p53 gain‐of‐function is thought to be mediated by interaction with other transcription factors. We identify multiple ETS transcription factors that can bind mutant p53 and found that this interaction can be promoted by a PXXPP motif. ETS proteins that strongly bound mutant p53 were upregulated in ovarian cancer compared to ETS proteins that ...
Stephanie A. Metcalf, Nicholas F. Downing, Kaitlyn M. Mills, Samuel C. Metcalfe, Alexander E. Kritzer, Lindsey D. Mayo, Peter C. Hollenhorst   +6 more
wiley   +1 more source

Conserved structural motifs in PAS, LOV, and CRY proteins regulate circadian rhythms and are therapeutic targets

FEBS Letters, EarlyView.
Cryptochrome and PAS/LOV proteins play intricate roles in circadian clocks where they act as both sensors and mediators of protein–protein interactions. Their ubiquitous presence in signaling networks has positioned them as targets for small‐molecule therapeutics. This review provides a structural introduction to these protein families.
Eric D. Brinckman, Anna E. Lester, Brian D. Zoltowski   +2 more
wiley   +1 more source

Backpressure-based control protocols: design and computational aspects [PDF]

, 2009
Congestion control in packet-based networks is often realized by feedback protocols. In this paper we assess their performance under a back-pressure mechanism that has been proposed and standardized for Ethernet metropolitan networks. In such a mechanism
Mandjes, M.R.H., Miretskiy, D.I., Scheinhardt, W.R.W.   +2 more
core   +2 more sources

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

FEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva, Ariann E. Mendoza‐Martínez, P. Abril Medina‐Flores, Carlos Campero‐Basaldua, Alexander DeLuna, Soledad Funes   +5 more
wiley   +1 more source

Application of Optimal Control to CPMG Refocusing Pulse Design

, 2010
We apply optimal control theory (OCT) to the design of refocusing pulses suitable for the CPMG sequence that are robust over a wide range of B0 and B1 offsets. We also introduce a model, based on recent progress in the analysis of unitary dynamics in the
Baum, Biercuk, Blume-Kohout, Bryson, Bãlibanu, Böhlen, Böhlen, Cappellaro, Carr, Chakrabarti, Choi, Connolly, David G. Cory, de Graaf, Ellett, Ernst, Fortunato, Freeman, Fu, Garwood, Geen, Glaser, Goelman, Havel, Havel, Hodges, Hwang, Hürlimann, Hürlimann, Khaneja, Khodjasteh, Kobzar, Kraus, Kupcé, Levitt, Luy, Mao, Martin D. Hürlimann, Meiboom, Meriles, Nielsen, Perlo, Pinch, Pontryagin, Pravia, Rabitz, Rosenfeld, Ryan, Sage, Skinner, Skinner, Skinner, Smith, Troy W. Borneman, Viola, Waugh   +55 more
core   +1 more source

Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions

FEBS Letters, EarlyView.
We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva, Puspa Kunwar, Md Ibnul Rifat Rahman, Joanna Koryo Kwao, Nathan Lehman, Zihan Zhang, Trenton Paul, Claire Cheng, Nicholas Truex, Hui‐Ting Lee, Jun Zhang   +10 more
wiley   +1 more source

Interface Design Temperature Control System Using Computer-based C Programming Language [PDF]

, 2004
Along with the development of science and technology, has had a positive impact in the industrial world, especially in the utilization of the temperature measurement system that uses the principle of data acquisition.
Kusumaningtyas, O. N. (Okti)
core