Results 11 to 20 of about 20,593,017 (308)

Bacteria as Control Engineers [PDF]

Molecular Cell, 2011
Bacteria encounter fluctuations in both their external and internal environments, and to manage these conditions, they employ various control mechanisms. In this issue of Molecular Cell, Hart et al. (2011) investigate how E. coli robustly controls nitrogen assimilation.
Allison, Kyle R., Collins, James J.
openaire   +2 more sources

Engineering control into medicine [PDF]

Journal of Critical Care, 2015
The human body is a tightly controlled engineering miracle. However, medical training generally does not cover "control" (in the engineering sense) in physiology, pathophysiology, and therapeutics. A better understanding of how evolved controls maintain normal homeostasis is critical for understanding the failure mode of controlled systems, that is ...
David J. Stone, Leo Anthony Celi, Marie Csete   +2 more
openaire   +2 more sources

Representation Engineering: A Top-Down Approach to AI Transparency [PDF]

arXiv.org, 2023
In this paper, we identify and characterize the emerging area of representation engineering (RepE), an approach to enhancing the transparency of AI systems that draws on insights from cognitive neuroscience.
Andy Zou, Long Phan, Sarah Chen, James Campbell, Phillip Guo, Richard Ren, Alexander Pan, Xuwang Yin, Mantas Mazeika, Ann-Kathrin Dombrowski, Shashwat Goel, Nathaniel Li, Michael J. Byun, Zifan Wang, Alex Troy Mallen, Steven Basart, Sanmi Koyejo, Dawn Song, Matt Fredrikson, Zico Kolter, Dan Hendrycks   +20 more
semanticscholar   +1 more source

An Introduction to Control Engineering [PDF]

Anaesthesia and Intensive Care, 1973
The viewpoint, terminology and technique of the control engineer are introduced in the context of biological control systems. The centrality of the feedback principle in the operation of control systems is emphasized, and the advantages of feedback control described. It is indicated that the control engineer frequently employs mathematical analysis and
openaire   +2 more sources

Review on model predictive control: an engineering perspective

The International Journal of Advanced Manufacturing Technology, 2021
Model-based predictive control (MPC) describes a set of advanced control methods, which make use of a process model to predict the future behavior of the controlled system.
M. Schwenzer, M. Ay, T. Bergs, D. Abel
semanticscholar   +1 more source

Introduction to the theory and technology on downhole control engineering and its research progress

Petroleum Exploration and Development, 2018
On the basis of reviewing the development history of drilling engineering technology over a century, this paper describes the technical and scientific background of downhole control engineering, discusses its basic issues, discipline frame and main study
Yinao Su
semanticscholar   +1 more source

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

FEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho, Shin Morioka, Junko Sasaki, Takehiko Sasaki   +3 more
wiley   +1 more source

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

FEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes, Guilherme M. Azevedo, Amanda P. Barcellos, Diana Bahia   +3 more
wiley   +1 more source

Responsibly Engineering Control

American Philosophical Quarterly
Abstract A number of concerns have been recently raised regarding the possibility of human agents to effectively maintain control over intelligent and (partially) autonomous artificial systems. These issues have been deemed to raise “responsibility gaps.” To address these gaps, several scholars and other public and private stakeholders ...
Köhler, S., Mecacci, G., Veluwenkamp, H.   +2 more
openaire   +3 more sources

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

FEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe, Tanmay Kumar Mohanty, Rashna Bhandari, Dorothea Fiedler   +3 more
wiley   +1 more source