Results 221 to 230 of about 4,537,045 (350)

Education in Control Engineering for the Designers of Environmental Processes

, 1994
E. Sroczan, Andrzej Urbaniak
openalex   +1 more source

A synthetic benzoxazine dimer derivative targets c‐Myc to inhibit colorectal cancer progression

Molecular Oncology, EarlyView.
Benzoxazine dimer derivatives bind to the bHLH‐LZ region of c‐Myc, disrupting c‐Myc/MAX complexes, which are evaluated from SAR analysis. This increases ubiquitination and reduces cellular c‐Myc. Impairing DNA repair mechanisms is shown through proteomic analysis.
Nicharat Sriratanasak, Bodee Nutho, Worawat Wattanathana, Narumon Phaonakrop, Bunnatut Panasawatwong, Katharina Erlenbach‐Wuensch, Sittiruk Roytrakul, Regine Schneider‐Stock, Pithi Chanvorachote   +8 more
wiley   +1 more source

Design and simulation of a PLC-controlled omni wheel conveyor sorting system for high-speed material handling. [PDF]

Sci Rep
Bhat R, Suresh S, Devakumar D, Subramanian KR, Dhanush D, Krishnan S.   +5 more
europepmc   +1 more source

Local control stations: Human engineering issues and insights

, 1994
W.S. Brown, J. Higgins, J. O'Hara
openalex   +1 more source

Adaptaquin is selectively toxic to glioma stem cells through disruption of iron and cholesterol metabolism

Molecular Oncology, EarlyView.
Adaptaquin selectively kills glioma stem cells while sparing differentiated brain cells. Transcriptomic and proteomic analyses show Adaptaquin disrupts iron and cholesterol homeostasis, with iron chelation amplifying cytotoxicity via cholesterol depletion, mitochondrial dysfunction, and elevated reactive oxygen species.
Adrien M. Vaquié, Davod R. Shah, Eliane E. S. Brechbühl, Michael McNicholas, Zhaoyang Xu, John H. Stockley, Laura Morcom, Diana Gold Diaz, Gemma C. Girdler, Rachel V. Seear, Gabriel Balmus, Rajiv R. Ratan, Harry Bulstrode, James A. Nathan, Manav Pathania, Kevin M. Brindle, David H. Rowitch   +16 more
wiley   +1 more source

Optical coherence elastography detects increased corneal stiffness in nonhuman primates with experimental glaucoma. [PDF]

J Biomed Opt
Singh A, Nair A, She Z, Dehshiri M, Singh M, Aglyamov S, Patel N, Larin K.   +7 more
europepmc   +1 more source

A study on the confidence limit for two independent probability variables in engineering problems. Applications to limit of transmitted torque in disk clutch and bolt axial tension control.

, 1990
Soichi Hareyama, Shotaro KODAMA
openalex   +2 more sources

Patient‐specific pharmacogenomics demonstrates xCT as predictive therapeutic target in colon cancer with possible implications in tumor connectivity

Molecular Oncology, EarlyView.
This study integrates transcriptomic profiling of matched tumor and healthy tissues from 32 colorectal cancer patients with functional validation in patient‐derived organoids, revealing dysregulated metabolic programs driven by overexpressed xCT (SLC7A11) and SLC3A2, identifying an oncogenic cystine/glutamate transporter signature linked to ...
Marco Strecker, Keren Zohar, Martin Böttcher, Thomas Wartmann, Henry Freudenstein, Maximilian Doelling, Mihailo Andric, Wenjie Shi, Or Kakhlon, Katrin Hippe, Beatrix Jahnke, Dimitrios Mougiakakos, Franziska Baenke, Daniel Stange, Roland S. Croner, Michal Linial, Ulf D. Kahlert   +16 more
wiley   +1 more source

Statistical prediction method of inclined shaft blasting fragmentation based on dynamic damage distribution in excavated rock mass. [PDF]

Sci Rep
Wei X, Shen Z, Song K, Qu D, Li X, Luo Y, Liu T.   +6 more
europepmc   +1 more source

An Engineering Approach to Controlling Indoor Air Quality

, 1991
James E. Woods
openalex   +1 more source