Results 231 to 240 of about 4,537,045 (350)

Predictors of response and rational combinations for the novel MCL‐1 inhibitor MIK665 in acute myeloid leukemia

Molecular Oncology, EarlyView.
This study characterizes the responses of primary acute myeloid leukemia (AML) patient samples to the MCL‐1 inhibitor MIK665. The results revealed that monocytic differentiation is associated with MIK665 sensitivity. Conversely, elevated ABCB1 expression is a potential biomarker of resistance to the treatment, which can be overcome by the combination ...
Joseph Saad, Rhiannon Newman, Elmira Khabusheva, Sofia Aakko, Eric Durand, Mahesh Tambe, Heikki Kuusanmäki, Alun Parsons, Juho J. Miettinen, Komal Kumar Javarappa, Ezgi June Olgac, Nemo Ikonen, Mika Kontro, Kimmo Porkka, Heiko Maacke, Janghee Woo, Ensar Halilovic, Caroline A. Heckman   +17 more
wiley   +1 more source

Double Profile Intersection (DoPIo) Ultrasound With Acoustic Radiation Force Tilting Interrogates Young's Modulus in Transversely Isotropic Media: An In Silico Study. [PDF]

IEEE Open J Ultrason Ferroelectr Freq Control
Muhtadi S, Yokoyama KA, Gallippi CM.
europepmc   +1 more source

ROBUSTNESS OF OPTIMAL OBSERVER/OPTIMAL CONTROL SYSTEM OF CIVIL ENGINEERING STRUCTURES

, 1990
Toshiaki Morimoto, Kohki Ninomiya, Shunsuke Baba   +2 more
openalex   +2 more sources

Feasibility of a ctDNA multigenic panel for non‐small‐cell lung cancer early detection and disease surveillance

Molecular Oncology, EarlyView.
Plasma‐based detection of actionable mutations is a promising approach in lung cancer management. Analysis of ctDNA with a multigene NGS panel identified TP53, KRAS, and EGFR as the most frequently altered, with TP53 and KRAS in treatment‐naïve patients and TP53 and EGFR in previously treated patients.
Giovanna Maria Stanfoca Casagrande, Marcela de Oliveira Silva, Mariana Bisarro dos Reis, Rodrigo de Oliveira Cavagna, Luciane Sussuchi, Icaro Alves Pinto, Natalia Zampieri Pontes, Rodrigo Sampaio Chiarantano, Flavio Augusto Ferreira da Silva, Pedro de Marchi, Letícia Ferro Leal, Rui M. Reis   +11 more
wiley   +1 more source

Evaluation of the mechanical behavior of concrete reinforced with waste tire steel fibers. [PDF]

Sci Rep
Oan AF, Attia F.
europepmc   +1 more source

Industrial engineering approach to new product development.2.Production control of new products.

, 1990
Shinroku Yamashita
openalex   +2 more sources

Characterizing epithelial‐mesenchymal transition‐linked heterogeneity in breast cancer circulating tumor cells at a single‐cell level

Molecular Oncology, EarlyView.
In over 50% of non‐metastatic breast cancer patients, circulating tumor cells (CTCs) along the whole epithelial‐mesenchymal transition spectrum are detected. Total CTC number and individual phenotypes relate to aggressive disease characteristics, including lymph node involvement and higher tumor proliferation. At the single‐cell level, mesenchymal CTCs
Justyna Topa, Julia Richert, Tomasz Stokowy, Alicja Staśczak, Mariusz Szajewski, Maciej Ciesielski, Petra M. Grešner, Bartłomiej Tomasik, Łukasz Arcimowicz, Agnieszka Stankiewicz, Grażyna Suchodolska, Elżbieta Senkus, Wiesław Kruszewski, Anna J. Żaczek, Aleksandra Markiewicz   +14 more
wiley   +1 more source

Bearing characteristics and control measures of coal rib under the condition of composite roof in deep mining. [PDF]

Sci Rep
Yang S, Wang X, Gu Q, Chen J.
europepmc   +1 more source

A control engineering approach to understanding the TGF-β paradox in cancer. [PDF]

J R Soc Interface, 2012
Chung SW, Cooper CR, Farach-Carson MC, Ogunnaike BA.   +3 more
europepmc   +1 more source

Special edition. Recent audio engineering. 2. Recent techniques of circuit and acoustic echo control for telephony.

, 1990
Shoji Shimada, Shoji Makino
openalex   +2 more sources