Results 261 to 270 of about 3,972,229 (347)

Indoleamine 2,3‐dioxygenase 1 inhibition reverses cancer‐associated fibroblast‐mediated immunosuppression in high‐grade serous ovarian cancer

FEBS Open Bio, EarlyView.
CAF‐mediated immunosuppression in ovarian cancer is driven by IDO1, reducing T‐cell function. Inhibiting IDO1 restores T‐cell proliferation and cytotoxicity, increases cancer cell apoptosis, and may help overcome CAF‐induced immune suppression in high‐grade serous ovarian cancer. Targeting IDO1 may improve antitumor immunity.
Hyewon Lee, Jung Yoon Ho, In Sun Hwang, Youn Jin Choi   +3 more
wiley   +1 more source

Normative surface electromyography values for the orbicularis oculi muscle in healthy control subjects. [PDF]

Sci Rep
Krajewska-Węglewicz L, Dorobek M.
europepmc   +1 more source

Thrombolytic proteins profiling: High‐throughput activity, selectivity, and resistance assays

FEBS Open Bio, EarlyView.
We present optimized biochemical protocols for evaluating thrombolytic proteins, enabling rapid and robust screening of enzymatic activity, inhibition resistance, and fibrin affinity, stimulation, and selectivity. The outcome translates to key clinical indicators such as biological half‐life and bleeding risk. These assays streamline the development of
Martin Toul, Alan Strunga, Jiri Damborsky, Zbynek Prokop   +3 more
wiley   +1 more source

Portable Lab for Shipping (POLS): A Biosensor-Based System for Rapid Onboard Detection of <i>Escherichia coli</i> and <i>Enterococcus</i> spp. in Ballast Water. [PDF]

Microorganisms
Agioti S, Loulakis E, Konstantinou L, Varda E, Inglezakis A, Loizou K, Apostolou T, Hadjilouka A.   +7 more
europepmc   +1 more source

Overview of molecular signatures of senescence and associated resources: pros and cons

FEBS Open Bio, EarlyView.
Cells can enter a stress response state termed cellular senescence that is involved in various diseases and aging. Detecting these cells is challenging due to the lack of universal biomarkers. This review presents the current state of senescence identification, from biomarkers to molecular signatures, compares tools and approaches, and highlights ...
Orestis A. Ntintas, Sylvia Vagena, Pavlos Pantelis, Giorgos Theocharous, Russel Petty, Konstantinos Evangelou, Vassilis G. Gorgoulis   +6 more
wiley   +1 more source

Radiometric and safety assessment of a 'low-level red-light' myopia control device. [PDF]

Ophthalmic Physiol Opt
Richards J, Hunter JJ, Gantes-Nuñez J, Bradley A, Kollbaum P.   +4 more
europepmc   +1 more source

Molecular determinants of signal transduction in tropomyosin receptor kinases

FEBS Open Bio, EarlyView.
Tropomyosin receptor kinases control critical neuronal functions, but how do the same receptors produce diverse cellular responses? This review explores the structural mechanisms behind Trk signaling diversity, focusing on allosteric modulation and ligand bias.
Giray Enkavi
wiley   +1 more source

Data from RNF185 Control of COL3A1 Expression Limits Prostate Cancer Migration and Metastatic Potential

Benjamin Van Espen, Htoo Zarni Oo, Colin C. Collins, Ladan Fazli, Alfredo Molinolo, Kevin Y. Yip, Rabi Murad, Martin Gleave, Ze’ev A. Ronai   +8 more
openalex   +1 more source

Control of open quantum systems and the quantum speed limit [PDF]

, 2012
Pablo M. Poggi, Fernando C. Lombardo, Diego A. Wisniacki   +2 more
openalex  

Long‐term culture of skin biopsies: maintenance of fibroblast production and competency of reprogramming

FEBS Open Bio, EarlyView.
Skin biopsies taken from a patient with an ultra‐rare disorder as well as controls were cultured for up to 473 days. The chunks of skin were serially transferred to a new culture plate when confluent with fibroblasts. Different generations of fibroblasts were analyzed for cell and molecular properties, proliferation, and competence for reprogramming to
Sudiksha Rathan‐Kumar, Michael A. Ripperger, Grant M. Westlake, Kevin C. Ess   +3 more
wiley   +1 more source