This study integrates publicly available transcriptomic datasets to identify molecular signatures associated with response to neoadjuvant chemoradiotherapy in locally advanced rectal cancer. By analyzing a combination of multiple cohorts with bioinformatics approaches, we reveal biological pathways and immune‐related features that may improve ...
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The VHL tumor suppressor at the crossroad of protein folding, aggregation, and cancer
Mutations, environmental stress, and chaperone dysfunction can destabilize pVHL, promoting its conversion from the native folded state into amyloid‐like assemblies. This transition may contribute to protein storage, cell dormancy, survival, and drug resistance.
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wiley +1 more source
Study on the Complex Electrical Response Characteristics of Loaded Coal and the Control Mechanism of the Main Fracture System Structure. [PDF]
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A tRNA-specific function for tRNA methyltransferase Trm10 is associated with a new tRNA quality control mechanism in Saccharomyces cerevisiae. [PDF]
Bowles IE, Jackman JE.
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Synthesis of lipid-linked precursors of the bacterial cell wall is governed by a feedback control mechanism in Pseudomonas aeruginosa. [PDF]
Marmont LS +10 more
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Plasma proteomics analysis of Chinese HIV-1 infected individuals focusing on the immune and inflammatory factors afford insight into the viral control mechanism. [PDF]
Ni W +9 more
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Mechanical linearization of mechanical control systems without controllability assumption
Automatica, 2023In this paper, the authors investigate on mechanical linearization of mechanical control systems without controllability assumption. More precisely, they present a linearization procedure of mechanical control systems that preserves the mechanical structure of the system, i.e., the mechanical linearization.
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This chapter is mainly concerned with functional imaging studies that illustrate different approaches to the study of control mechanisms. The prefrontal cortex does not act by itself. The executive properties of prefrontal cortex emerge through interactions with other brain areas.
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