Results 241 to 250 of about 15,001,366 (306)

Profiling neoadjuvant therapy response in rectal cancer using meta‐analysis of publicly available transcriptomic RNA‐seq datasets

open access: yesMolecular Oncology, EarlyView.
This study integrates publicly available transcriptomic datasets to identify molecular signatures associated with response to neoadjuvant chemoradiotherapy in locally advanced rectal cancer. By analyzing a combination of multiple cohorts with bioinformatics approaches, we reveal biological pathways and immune‐related features that may improve ...
Aleksandra Stanojevic   +10 more
wiley   +1 more source

The VHL tumor suppressor at the crossroad of protein folding, aggregation, and cancer

open access: yesMolecular Oncology, EarlyView.
Mutations, environmental stress, and chaperone dysfunction can destabilize pVHL, promoting its conversion from the native folded state into amyloid‐like assemblies. This transition may contribute to protein storage, cell dormancy, survival, and drug resistance.
Lara Abad   +2 more
wiley   +1 more source

Synthesis of lipid-linked precursors of the bacterial cell wall is governed by a feedback control mechanism in Pseudomonas aeruginosa. [PDF]

open access: yesNat Microbiol
Marmont LS   +10 more
europepmc   +1 more source
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Mechanical linearization of mechanical control systems without controllability assumption

Automatica, 2023
In this paper, the authors investigate on mechanical linearization of mechanical control systems without controllability assumption. More precisely, they present a linearization procedure of mechanical control systems that preserves the mechanical structure of the system, i.e., the mechanical linearization.
Marcin Nowicki, Witold Respondek
openaire   +2 more sources

Mechanisms of Control

2004
This chapter is mainly concerned with functional imaging studies that illustrate different approaches to the study of control mechanisms. The prefrontal cortex does not act by itself. The executive properties of prefrontal cortex emerge through interactions with other brain areas.
Chris D, Frith   +2 more
openaire   +1 more source

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