Results 111 to 120 of about 12,023,497 (300)

Uncoupling Type I Interferon Benefits From Inflammatory Toxicity: Transformer‐Prioritized Precision Agonists for Potent and Safer Cancer Immunotherapy

Advanced Science, EarlyView.
A Transformer‐based AI framework, DLINP, screens millions of compounds to identify Co68, a cobalt‐pincer organometallic complex that biases TLR4‐MD2 signaling toward antitumor interferon activation while suppressing inflammatory toxicity through an early TLR4‐SYK‐STAT1 axis.
Xuefei Guo, Yang Zhao, Xianle Rong, Xingyu Chen, Xiao Wang, Tianyi Liu, Yunfei Xie, Yushu Zou, Pingsen Zhao, Qiang Liu, Fuping You   +10 more
wiley   +1 more source

HCV RNA positivity among hepatitis C patients in Chongqing, China from 2004 to 2021: a cross-sectional study

BMC Infectious Diseases
Background A substantial number of hepatitis C virus (HCV) infections have been diagnosed and reported, yet not all reported patients have received treatment, leading to uncertainties in the progression of the virus within these cases.
Yaping He, Shaodong Ye, Wei Zhang, Rongrong Lu, Jing Lin, Chao Zhou, Guohui Wu   +6 more
doaj   +1 more source

Estimation of genotoxicity threshold induced by acute exposure to neodymium nitrate in mice using benchmark dose

环境与职业医学
Background The benchmark dose (BMD) method calculates the dose associated with a specific change in response based on a specific dose-response relationship. Compared with the traditional no observed adverse effect level (NOAEL) method, the BMD method has
Junli LIU, Yu DING, Xueqing CHENG, Zhengli YANG, Kelei QIAN, Jing XU, Yiyun FAN, Dongsheng YU, Zhiqing ZHENG, Jun YANG, Ning WANG, Xinyu HONG   +11 more
doaj   +1 more source

Bio‐Inspired Oligocellulose‐Regulated Ice‐Water Interfaces Enable Sustained Ion Transport in Frozen Aqueous Zinc Batteries

Advanced Science, EarlyView.
Inspired by antifreeze glycoproteins (AFGPs), we synthesized a type of oligomeric cellulose (OC‐8) to inhibit ice formation and enlarge the inter‐ice water channel for transportation. Typical confocal fluorescence experiments display the expansion of the ice‐water interface for zinc‐ion transport.
Zeyu Zhu, Jingxuan Pan, Haoran Ma, Boya Yuan, Cristina Carucci, Sunghak Park, Chong Gao, Minmin Liang, Kaiqi Li, Wei Li, Dan Wang, Xiaoting Chen, Zhiyuan He   +12 more
wiley   +1 more source

Screening of close contacts of pulmonary tuberculosis in an urban area in Shanghai, China: a cross-sectional study

BMC Infectious Diseases
Objectives The study aimed to explore the risk factors of close contacts developing pulmonary tuberculosis (TB), identify active TB and describe the sociodemographic characteristics of active TB among close contacts in Putuo District, Shanghai.
Shiqi Zhang, Fen Li, Jing Chen, Zheyuan Wu, Chenxi Ning, Xin Shen, Zhengan Yuan   +6 more
doaj   +1 more source

Low SLC8A1 in Colorectal Cancer Dictates Radiotherapy Resistance Through Calcium‐Dependent ANXA2+sEVs Driving M2 Polarization of TAMs

Advanced Science, EarlyView.
SLC8A1 deficiency in colorectal cancer cells increases intracellular calcium signaling, promoting the secretion of ANXA2‐enriched small extracellular vesicles. These vesicles reprogram tumor‐associated macrophages towards an M2 phenotype, which in turn fosters a tumor microenvironment conducive to radioresistance and is associated with poor patient ...
Yimin Fang, Jinghan Zhu, Qian Xiao, Qichun Wei, Xiujing He, Ping Li, Kai Jiang, Yue Liu, Yeting Hu, Weiwei Yu, Chuansheng Guo, Sheng Chen, Jian Zhao, Siqi Dai, Jingsun Wei, Hang Yang, Tongtong Bu, Kefeng Ding, Haiyan Chen   +18 more
wiley   +1 more source

Relació de llocs de treball (RLT) de l'Institut Municipal d'Hisenda de Barcelona [2019] : modificació [2022-09-27]

, 2022
Aprovat pel Consell Rector de l'Institut Municipal d'Hisenda de 27-09 ...
Institut Municipal d'Hisenda (Barcelona)
core  

Efficient Cholesteric Liquid Crystal Waveguide Polarizing Splitters for High‐Sensitivity Chip‐Scale Atomic Magnetometry

Advanced Science, EarlyView.
An integrated polarimetry architecture based on a cholesteric liquid crystal waveguide polarization splitter overcomes the volumetric bottleneck in chip‐scale atomic magnetometers. By leveraging Bragg‐selective reflection and total‐internal‐reflection‐induced helicity inversion, this ultrathin device enables efficient circular polarization splitting ...
Zhibo Cui, Chuang Wang, Xiangyang Zhou, Gaopu Hou, Jinsheng Hu, Mao Ye, Xu Xiao, Zhen Chai, Yishi Weng, Yuning Zhang   +9 more
wiley   +1 more source

Relació de llocs de treball (RLT) de l'Institut Municipal d'Educació de Barcelona [2019] : modificació [2022-10-21]

, 2022
Aprovada per el Consell Rector de l'Institut Municipal d'Educació de Barcelona de 21-10 ...
Institut Municipal d'Educació (Barcelona)
core  

Exploring the practice of integrated community chronic disease management model in Shanghai

Guangxi Yike Daxue xuebao
The aggravation of population aging has made the pressure of chronic disease prevention and treatment increasingly prominent and faced unprecedented challenges.
CHENG Minna, SUI Mengyun, ZHANG Sheng, ZHENG Yang, GU Kai, YANG Qundi, RUAN Ye, WANG Yuheng, YAN Qinghua, YANG Qinping, FU Chen, YU Rong, SHI Yan   +12 more
doaj   +1 more source