Results 121 to 130 of about 168,817,331 (301)

Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer

Molecular Oncology, EarlyView.
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola, Yasmine Illi, Anna Bircher, Marijn Wilmink, Rachele F. Malagutti, Solenn Ottié, Cordelia Schuler, Pedro A. Ruiz, Cheryl de Vallière, Klaus Seuwen, Gerhard Rogler, Martin Hausmann   +11 more
wiley   +1 more source

Guidelines for the prevention and treatment of opportunistic infections in adults and adolescents with HIV [PDF]

Developed by the National Institutes of Health, the Centers for Disease Control and Prevention, and the HIV Medicine Association of the Infectious Diseases Society of America Panel on Guidelines for the Prevention and Treatment of Opportunistic ...

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In vitro and in silico modelling of ROS1‐positive non‐small cell lung cancer reveals fusion‐dependent tyrosine kinase inhibitor responses

Molecular Oncology, EarlyView.
Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq, Marc Terrones, Felicia Rodrigues Fortes, Anne Schepers, Alessia Denis, Christophe Deben, Ken Op de Beeck, Guy Van Camp, Geert Vandeweyer   +8 more
wiley   +1 more source

Other title: Healthcare Associated Infections annual report; Other title: Report to the legislature concerning the status of the Healthcare Associated Infections Initiative

, 2013
Annual; Began with Oct. 1, 2008.; "An Act Concerning Hospital Acquired Infections."; At head of title: State of Connecticut.; Volume for Oct.
Healthcare Associated Infections Program (Conn.)
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PANoptosis in the pathogenesis of myelodysplastic syndromes

Molecular Oncology, EarlyView.
PANoptosis, a combination of three types of programmed cell death, is mediated by a large protein complex called a PANoptosome. In healthy bone marrow hematopoietic cells, PANoptosis is restricted by inhibitory signaling. In MDS, bone marrow cells become sensitive to the PANoptotic stimuli due to the aberrant inactivation of inhibitory signaling or ...
Rohit Thalla, Jyoti Lamichhane, Cameron Lewis, Peter Breslin, Jiwang Zhang   +4 more
wiley   +1 more source

Synthetic Peptides as a Promising Alternative to Control Viral Infections in Atlantic Salmon. [PDF]

Pathogens, 2020
Cárdenas C, Guzmán F, Carmona M, Muñoz C, Nilo L, Labra A, Marshall SH.   +6 more
europepmc   +1 more source

Guide: Monitoring Programme for unannounced inspections undertaken against the National Standards for the Prevention and Control of Healthcare Associated Infections

, 2014
This is a guide to the Health Information and Quality Authority?s (the Authority) programme of monitoring service providers? compliance with the National Standards for the Prevention and Control of Healthcare Associated Infections (referred to in this ...

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Somatostatin receptor 4 (SSTR4) is a tumor suppressor in cutaneous and head & neck squamous cell carcinomas

Molecular Oncology, EarlyView.
This study identifies somatostatin receptor 4 (Sstr4) as a critical tumor suppressor against skin and head/neck cancers (HNSCC, cSCC, and BCC). The loss of Sstr4 removes a check on cell growth, causing hyperactivation of the MAPK‐ERK signaling pathway (↑).
Ali Taqvi, Tuan Khang Huynh, Adway Kadam, Zahra Kardan, Yue Yan, Amina Jamal Laham, Sampath Kumar Loganathan   +6 more
wiley   +1 more source

Elderly individuals exhibit dysregulated monocyte responses to viral immune complexes compared to adults and children

Scientific Reports
The severity of certain viral infectious diseases varies across the age; we hypothesize that these variations could be related to the variation of immune responses to viral immune complexes (ICs) among the age.
Léa Domitien Payet, Anthony Coléon, Anne Sophie Bedin, Lucas Auguste, Maël Morvan Duroyon, Caroline Mollevi, Hubert Blain, Franck Mennechet, Éric Jeziorski, Édouard Tuaillon   +9 more
doaj   +1 more source

Glycemic Control and Infections Among US Hemodialysis Patients With Diabetes Mellitus. [PDF]

Kidney Int Rep, 2020
Rhee JJ, Zheng Y, Liu S, Montez-Rath ME, Hamill RJ, Ishida JH, Winkelmayer WC.   +6 more
europepmc   +1 more source