Results 121 to 130 of about 1,989,439 (263)

Layers of exposure risk management measures for the prevention and control of infections of healthcare workers treating COVID-19 patients. [PDF]

PLoS One
Andrei NȘ, Elena-Sabina T, Silviu-Mihail T, Ana-Iolanda V, Vladimir P.   +4 more
europepmc   +1 more source

Saline Environments as a Source of Potential Quorum Sensing Disruptors to Control Bacterial Infections: A Review. [PDF]

Mar Drugs, 2019
Torres M, Dessaux Y, Llamas I.
europepmc   +1 more source

Mutant p53R273H disrupts PDPK1 homodimerization and contributes to PDPK1 activation

Molecular Oncology, EarlyView.
How mutant p53R273H drives AKT signaling is unclear. We show that p53R273H, but not wild‐type, directly binds PDPK1 via a mutation‐dependent conformational change. This interaction disrupts inhibitory PDPK1 homodimerization and enhances AKT phosphorylation.
Mei Chee Lim, Alvin Kunyao Guo, Yoko Itahana, Srinivasaraghavan Kannan, Valerie Goh, Mingmin Ong, Terina Yan Wen Tay, Weiying Ye, Sabhashina Radha Krishnan, Jun Nishiyama, Chandra S Verma, Koji Itahana   +11 more
wiley   +1 more source

Epidemic characteristics of measles and efforts to control measles infections in Zhejiang Province, China. [PDF]

Epidemiol Health
Yan R, Yang M, He H, Feng Y, Zhou Y, Tang X, Deng X, Zhu Y, Du Y, Chen C, Kexin C, Yang S, RIDPHE Group.   +12 more
europepmc   +1 more source

Directed evolution of enzymes at the crossroads of tradition and innovation

FEBS Open Bio, EarlyView.
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova, Andrej Mirossay, Erik Sedlak   +2 more
wiley   +1 more source

Combined prevention and treatment measures are essential to control nosocomial infections during the COVID-19 pandemic. [PDF]

World J Virol
Liu JW, Li YY, Wang MK, Yang JS.
europepmc   +1 more source

Molecular characterization of covRS mutations in M1UK Streptococcus pyogenes

FEBS Open Bio, EarlyView.
Group A Streptococcus (GAS) acquires covRS mutations driving a hypervirulent bacterial state, frequently associated with invasive disease‐like necrotizing fasciitis. We demonstrate that the newly emerged M1UK GAS lineage can also acquire these mutations.
Jarrad Pritchard, Emma‐Jayne Proctor, Jiawa Wang, Nikolas P. Johnston, Andrew Hayes, Georgia McCorkell, Haibo Yu, Jai Tree, Mark R. Davies, Mark J. Walker, Ronald Sluyter, Stephan Brouwer, Martina L. Sanderson‐Smith   +12 more
wiley   +1 more source

New Perspectives on the Use of Phytochemicals as an Emergent Strategy to Control Bacterial Infections Including Biofilms. [PDF]

Molecules, 2016
Borges A, Abreu AC, Dias C, Saavedra MJ, Borges F, Simões M.   +5 more
europepmc   +1 more source

Evaluating the involvement of autolysosomes in the nuclear translocation of fluorescent proteins

FEBS Open Bio, EarlyView.
Endogenously expressed fluorescent proteins can be degraded by autophagy and transported to cell nuclei via the nuclear pore complex. But in some cell lines, for example, HeLa cells which are positive for immunoreactivity of a receptor ligand, such as UCN I, in cell nuclei, fusion of autolysosome with the nuclear envelope is involved in the nuclear ...
Keiichi Ikeda
wiley   +1 more source

Antimicrobial photodynamic therapy: an effective alternative approach to control fungal infections. [PDF]

Front Microbiol, 2015
Baltazar LM, Ray A, Santos DA, Cisalpino PS, Friedman AJ, Nosanchuk JD.   +5 more
europepmc   +1 more source