Improving the control of a robot for eye surgery
This report is the result of an internship at the Engineering Research Center for Computer Integrated Surgical Systems and Technology at the Johns Hopkins University in Baltimore, Maryland, USA.
Meerwaldt, T.T. +2 more
core
Next-generation microneedle patches for transdermal therapeutics and diagnostics. [PDF]
Chen TH +8 more
europepmc +1 more source
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla +9 more
wiley +1 more source
Multilevel Determinants of Acromiohumeral Distance Within a Systems-Based Functional Morphology Framework and Their Implications for Personalized Neuromusculoskeletal Modelling. [PDF]
Arráez-Aybar LA +3 more
europepmc +1 more source
KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan +16 more
wiley +1 more source
Design and performance evaluation of a solar powered remote controlled robot for precision seed planting. [PDF]
Aboharg S +5 more
europepmc +1 more source
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary +1 more
wiley +1 more source
Research on the Angle Measurement Accuracy of Laser Seekers Based on Electrowetting Dual-Liquid Dynamic Zoom Systems. [PDF]
Yao Y, Zheng R, Wang L, Qiao J.
europepmc +1 more source
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska +13 more
wiley +1 more source
Mechanical and Microstructural Performance of Different Plaster Mortars Used to Protect Interior Concrete Exposed to Elevated Temperatures. [PDF]
Türkmen İ +4 more
europepmc +1 more source

