Results 171 to 180 of about 19,092,455 (347)
From mice to humans—divergent strategies for intestinal homeostasis and regeneration
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa +2 more
wiley +1 more source
Phosphoinositides and inositol phosphates as molecular glues
Inositol phosphates (IPs) and phosphoinositides (PIPs) regulate diverse eukaryotic processes. Beyond recruiting signaling proteins or acting as structural cofactors, recent studies suggest they mediate protein–protein interactions as natural molecular glues.
Aleshia Seaton‐Terry +9 more
wiley +1 more source
This paper describes the work developed for the laboratorial implementation of an Active Mass Damper (AMD) to reduce the levels of vibration of a plane frame physical model excited by several kinds of loads, in particular seismic loads. For this purpose,
E. Caetano, C. Moutinho, A. Cunha
core
Study the Stability of a Wastewater Treatment Unit using LABVIEW
This study was devoted to limit the stability conditions of the wastewater treatment unit. LABVIEW was a powerful and versatile graphical programming language in automation control and date acquisition of the system.
Ghainm M. Alwan, Farooq A. Mehdi
doaj
Drosophila park mutants serve as a model for Parkinson's disease. We used this strain to investigate the connection between oxidative stress and the circadian clock mechanism. We showed that increased oxidative stress affects the physiology of pacemaker cells, disrupting their daily structural plasticity. Lack of rhythmic signaling from pacemaker cells
Kamila Zientara +3 more
wiley +1 more source
On offloading control plane applications to the data plane
One of the most active areas in computer networking is Software Defined Networking (SDN). SDN separates the two core functions of a network element (e.g., router): the control-plane and the data-plane. Traditionally both these functions were implemented on the same device; SDN decouples them, and allows multiple control-plane implementations for ...
openaire +1 more source
Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee +7 more
wiley +1 more source
A survey: Control plane scalability issues and approaches in Software-Defined Networking (SDN)
Murat Karakus, A. Durresi
semanticscholar +1 more source
Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley +1 more source
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens +8 more
wiley +1 more source

