Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers
This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel +6 more
wiley +1 more source
A graphical user interface for flight control development
The FSA (First Shot Approach) Demonstrator of DLR and DASA/Airbus is a first prototype for an integrated multidisciplinary environment for flight control developement.
Finsterwalder, Reinhard +2 more
core
Effect of Phantom Containing Implants Angulation on the Amount of Metal Artifacts Around the Implants in CBCT Images. [PDF]
Valizadeh S +5 more
europepmc +1 more source
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano +6 more
wiley +1 more source
DIAGRAMS, FUNCTIONAL AND CONSTRUCTIVE SOLUTIONS OF THE STABILITY CONTROL SYSTEMS FOR AUTOMOTIVE APPLICATION [PDF]
The modern car must correspond to certain requirements regarding the driver safety and more than that it must convince the potential buyer that it will offer him the safety he is so much in need of.
OANA-CARMEN Niculescu-Faida
core
An Exploration of Craniofacial Features in Obstructive Sleep Apnea Using the Explainable Deep Learning Approaches. [PDF]
Luo L +7 more
europepmc +1 more source
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson +9 more
wiley +1 more source
Jun Wu +4 more
semanticscholar +1 more source
Serratus Posterior Superior Intercostal Plane Block and Serratus Anterior Plane Block Compared with Conventional Analgesia for Postoperative Analgesia in Breast Cancer Surgery: A Randomized Controlled Trial. [PDF]
Baytar MS +4 more
europepmc +1 more source
COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells
This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos +6 more
wiley +1 more source

