Results 211 to 220 of about 16,569,160 (252)

Hyperactive ice‐binding proteins stabilize cell membranes and improve resistance to dehydration stress in Caenorhabditis elegans

FEBS Open Bio, EarlyView.
TisIBP8, a fungal‐derived hyperactive ice‐binding protein, helps Caenorhabditis elegans survive dehydration. It localizes near cell membranes, reduces cell damage, and helps maintain membrane structure during drying. These results suggest that ice‐binding proteins can protect cells from dehydration stress as well as freezing stress.
Daiki Shimose, Kotaro Ozaki, Ryohei Kuriyama, Yuka Ikemoto, Kazuhiro Mio, Yuji C. Sasaki, Tatsuya Arai, Sakae Tsuda, Yoichi Shinkai, Masahiro Kuramochi   +9 more
wiley   +1 more source

Effect of quality control program on surgical management in advanced ovarian cancer. [PDF]

J Gynecol Oncol
Kim BR, Ko H, Son D, Shim JE, Kim YH.
europepmc   +1 more source

Hyperosmotic stress‐induced redistribution of pre‐mRNA cleavage factor I subunits is associated with shifts in alternative polyadenylation

FEBS Open Bio, EarlyView.
Hyperosmotic stress triggers the relocation of the CFIm complex from the nucleus to the cytoplasm. This shift creates a nuclear ‘stoichiometric bottleneck’, limiting CFIm availability for mRNA processing. Consequently, specific mRNAs like NUDT21 and DICER1 undergo targeted 3′UTR shortening, demonstrating how spatial protein dynamics drive rapid ...
Hitomi Soumiya, Masatake Osawa, Hidefumi Fukumitsu   +2 more
wiley   +1 more source

Assessment of national tobacco control program (NTCP) initiative on tobacco cessation among transgenders in Puducherry - A quasi-experimental study. [PDF]

J Family Med Prim Care
Sidhu L, Kumar S, Ragavane P, Chandrasekaran P, Murugappan S.   +4 more
europepmc   +1 more source

Loss of AMBRA1 activates MAPK and angiogenesis signaling pathways in melanoma cells

FEBS Open Bio, EarlyView.
Loss of AMBRA1 in melanoma cells activates multiple oncogenic pathways associated with tumor progression. Transcriptomic and protein network analyses revealed that AMBRA1 depletion enhances MAPK/ERK signaling, angiogenesis, TGF‐β/EMT signaling, and Wnt/axon guidance pathways.
Milad Ibrahim, Marco Corazzari, Iman Osman, Jane Armstrong, Noel Carter   +4 more
wiley   +1 more source

Contextual barriers to infection prevention and control program implementation in hospitals in Latin America: a mixed methods evaluation. [PDF]

Antimicrob Resist Infect Control
Fabre V, Secaira C, Herzig C, Bancroft E, Bernachea MP, Galarza LA, Aquiles B, Arauz AB, Bangher MDC, Bernan ML, Burokas S, Canton A, Cazali IL, Colque A, Comas M, Contreras RV, Cornistein W, Cordoba MG, Correa SM, Campero GC, Chamorro Ayala MI, Chavez N, De Ascencao G, García CC, Esquivel C, Ezcurra C, Fabbro L, Falleroni L, Fernandez J, Ferrari S, Freire V, Garzón MI, Gonzales JA, Guaymas L, Guerrero-Toapanta F, Laplume D, Lambert S, Lemir CG, Lazarte PR, Lopez IL, Maldonado H, Martínez G, Maurizi DM, Mesplet F, Moreno Izquierdo C, Moya GL, Nájera M, Nuccetelli Y, Olmedo A, Palacio B, Pellice F, Raffo CL, Ramos C, Reino F, Rodriguez V, Romero F, Romero JJ, Sadino G, Sandoval N, Suarez M, Suayter MV, Ureña MA, Valle M, Vence Reyes L, Perez SVA, Videla H, Villamandos S, Villarreal O, Viteri MA, Warley E, Quiros RE.   +70 more
europepmc   +1 more source

Effects of IGFBP4 deficiency on human preadipocyte proliferation and differentiation through the IGF1R/AKT pathway

FEBS Open Bio, EarlyView.
IGFBP4 knockdown (KD) impairs preadipocyte proliferation and is associated with IGF1R protein downregulation and attenuated AKT phosphorylation. The mechanisms by which IGFBP4 KD influences the IGF1R/AKT signaling pathway involve newly synthesized proteins and lysosomal degradation pathways. Created in BioRender.
Yujia Guo, Sandy Richter, Christoph Bach, Wieland Kiess, Anna Kirstein, Diana Le Duc, Antje Garten   +6 more
wiley   +1 more source

Determination and Characterization of (Novel) Circulating Strains of <i>Brucella</i> sp. Within the National Bovine Brucellosis Control Program in Ecuador. [PDF]

Pathogens
Garrido-Haro AD, Falconí M, Moreno-Caballeros P, Elena-Rovalino M, Rosero-Mayanquer H, Yugcha-Díaz M, Fretin D, Wielick C, Saegerman C, Ron-Román J.   +9 more
europepmc   +1 more source

Treatment with KCL‐286, a first‐in‐class retinoic acid receptor‐β (RARβ) agonist, ameliorates neuronal DNA damage and inflammation in a mouse model of Alzheimer's disease

FEBS Open Bio, EarlyView.
Repair of neuronal DNA damage in Alzheimer's disease by KCL‐286. (A) Amyloid‐β oligomers and plaques impair neuronal DNA repair pathways, leading to DNA double‐strand breaks and glial activation. (B) KCL‐286 activates RARβ/RXR signalling via retinoic acid response elements (RAREs), associated with increased BRCA1 expression, enhanced DNA repair and ...
Natasha Hill, Hassan Yousef Othman AlMuallim, Elouisa Maddock, Carl Hobbs, Earl Clarke, Maria B. Goncalves, Jonathan P. T. Corcoran   +6 more
wiley   +1 more source

Assessment of Vaccination Impact in PPR-Control Program Implemented in Southern States of India: A System Dynamics Model Approach. [PDF]

Viruses
Gurrappanaidu G, Subbanna NKG, Wanyoike F, Bahta S, Reddy YR, Bardhan D, Vinayagamurthy B, Vijayalakshmy K, Habibur R.   +8 more
europepmc   +1 more source