Results 141 to 150 of about 3,051,873 (249)

Exploring Human Papillomavirus 16 Long Control Region Variants in Paraguayan Women: Comparing Variant Diversity to Transcriptional Activity and Cervical Lesion Severity. [PDF]

Int J Microbiol
Mongelós P, Martínez M, Díaz N, Nunes VT, Valenzuela Cáceres A, Mercado-Amarilla A, Miranda M, Bernal L, Kasamatsu E, Páez M, Castro A, Rodriguez-Riveros MI, Barrios H, Baena A, Rol M, Almonte M, Herrero R, Sichero L, Mendoza L.   +18 more
europepmc   +1 more source

Genetic diversity of E6, E7 and the long control region in human papillomavirus type 16 variants in Beijing, China. [PDF]

Biochem Biophys Rep, 2022
Wang J, Guo Y, Wang H, Li Y, Zhang L, Wang Z, Song L, Liu H.   +7 more
europepmc   +1 more source

Pharmacological chromatin remodeling enhances response to estrogen therapy in ER+ breast cancer

Molecular Oncology, EarlyView.
Estrogen therapy elicits clinical benefit in ~ 30% of patients with endocrine‐resistant estrogen receptor (ER)‐positive breast cancer. Based on findings that ER transcriptional activation underlies response to estrogen therapy, we tested the effects of epigenetic dysregulation via pharmacological inhibition of histone deacetylases (HDACi).
Anneka L. Johnson Thomas, Barbara Karakyriakou, Patricia C. Muskus, Alyssa M. Roberts, Justin Rendleman, Alexa Warren, Hanxu Lu, Kimberly A. Birmingham, Malone K. Friedman, Abigail E. Goen, Huijuan Yang, Owen M. Wilkins, Fred W. Kolling, Eugene Demidenko, Julie M. Jorns, Brock C. Christensen, Todd W. Miller   +16 more
wiley   +1 more source

The conserved noncoding sequence CNS11 is a master control region for <i>Rorc</i> transcription in type 17 immune cells. [PDF]

Sci Adv
Zhang H, Chang D, Xie S, Li R, Zhang Q, Xing Q, Xie T, Zhang G, Lou X, Li S, Yang L, Dong V, Ge J, Wang X, Dong C.   +14 more
europepmc   +1 more source

Intrapatient tumour heterogeneity and clonal evolution in an autopsy study of metastatic salivary gland cancer

Molecular Oncology, EarlyView.
Tumour heterogeneity and clonal evolution of metastatic salivary gland cancer were evaluated in two patients with adenoid carcinoma and one patient with myoepithelial carcinoma. Radiology‐guided autopsy enabled multi‐region sampling (total samples n = 149), followed by whole‐genome sequencing and phylogenetic reconstruction (17 tumour samples, 4–7 per ...
Gerben Lassche, Niels J. van Ruitenbeek, Charlotte Adang, Luke O'Gorman, Pui Yuen Lee, Willemijn M. Klein, Adriana C. H. van Engen‐van Grunsven, Jack A. Schalken, Sander Bervoets, Gerald W. Verhaegh, Carla M. L. van Herpen   +10 more
wiley   +1 more source

Complete Mitochondrial Genomes of Five Racerunners (Lacertidae: Eremias) and Comparison with Other Lacertids: Insights into the Structure and Evolution of the Control Region. [PDF]

Genes (Basel), 2022
Tian L, Guo X.
europepmc   +1 more source

The structure of a controllability region

, 2020
ZVERKIN A.M., ROZOVA V.N.
openaire   +2 more sources

Somatostatin receptor 4 (SSTR4) is a tumor suppressor in cutaneous and head & neck squamous cell carcinomas

Molecular Oncology, EarlyView.
This study identifies somatostatin receptor 4 (Sstr4) as a critical tumor suppressor against skin and head/neck cancers (HNSCC, cSCC, and BCC). The loss of Sstr4 removes a check on cell growth, causing hyperactivation of the MAPK‐ERK signaling pathway (↑).
Ali Taqvi, Tuan Khang Huynh, Adway Kadam, Zahra Kardan, Yue Yan, Amina Jamal Laham, Sampath Kumar Loganathan   +6 more
wiley   +1 more source

Internal Validation of a Mitochondrial DNA Control Region Sequencing Workflow Using Precision ID mtDNA Whole Genome Panel, Ion Chef™ System and Ion S5™ XL System. [PDF]

Genes (Basel)
Shue BH, Tay AS, Pook SH, Hoe SY, Loh KJ, Syn CK.   +5 more
europepmc   +1 more source

Epigenetic mosaicism and cell burden in Beckwith-Wiedemann syndrome due to loss of methylation at imprinting control region 2. [PDF]

Cold Spring Harb Mol Case Stud, 2021
Duffy KA, Hathaway ER, Klein SD, Ganguly A, Kalish JM.   +4 more
europepmc   +1 more source