Results 161 to 170 of about 3,051,873 (249)

Unraveling the genetic connections for mitochondrial DNA control region and breast cancer susceptibility. [PDF]

Sci Rep
Khalid N, Khan MU, Rehman R, Kanwal S, Zahid T, Ghani MU, Iftikhar A, Ali Q, Javed MA.   +8 more
europepmc   +1 more source

The mitochondrial genome of Faughnia haani (Stomatopoda): novel organization of the control region and phylogenetic position of the superfamily Parasquilloidea. [PDF]

BMC Genomics, 2021
Hwang HS, Jung J, Baeza JA.
europepmc   +1 more source

APOBEC3 activity and DNA polymerase‐ε deficiency are associated with distinct IDH1 R132 hotspot mutations

Molecular Oncology, EarlyView.
Isocitrate dehydrogenase 1 (IDH1) mutations are highly recurrent in multiple human cancer types, including cholangiocarcinoma and glioma. IDH1 R132C is the most common IDH1 mutation in cholangiocarcinoma and likely arises from APOBEC3A‐ or APOBEC3B‐mediated deamination.
Kelly E. Butler, Bilal A. Lone, Ecem Unal, A. Rouf Banday   +3 more
wiley   +1 more source

The Complete Mitochondrial Genome of the Deep-Dwelling Goby <i>Suruga fundicola</i> (Teleostei, Gobiidae) Reveals Evidence of Recombination in the Control Region. [PDF]

Int J Mol Sci
An C, Li A, Wang H, Che S, van der Laan R, Liu S, Zhuang Z.   +6 more
europepmc   +1 more source

Gene variation and population structure of Pampus chinensis in the China coast revealed by mitochondrial control region sequences. [PDF]

Mitochondrial DNA B Resour, 2021
Sun P, Yu J, Tang B, Liu Z.
europepmc   +1 more source

p190A/ARHGAP35 and p190B/ARHGAP5 proteins in endometrial cancer: a novel cancer‐relevant paralog interplay

Molecular Oncology, EarlyView.
This study identifies ARHGAP5, in addition to the frequently mutated ARHGAP35, as significantly mutated in endometrial cancer. Mutations in both genes co‐occur and are associated with their correlated downregulation. Functional CRISPR studies show that both paralogs regulate similar pathways, including actin cytoskeleton organization.
Mathilde Pinault, Capucine Heraud, Mélissa Correia de Oliveira, Véronique Neaud, Valérie Valesco, Valérie Prouzet‐Mauleon, Béatrice Turcq, Jean‐William Dupuy, Anne‐Aurélie Raymond, Sabrina Croce, Frédéric Saltel, Valérie Lagrée, Violaine Moreau   +12 more
wiley   +1 more source

Mitochondrial Control Region Database of Hungarian Fallow Deer (Dama dama) Populations for Forensic Use. [PDF]

Animals (Basel)
Zorkóczy OK, Wagenhoffer Z, Lehotzky P, Pádár Z, Zenke P.   +4 more
europepmc   +1 more source

Bridging the gap: a genetically validated avian chorioallantoic membrane platform for investigation of spontaneous circulating tumor cells

Molecular Oncology, EarlyView.
We established the avian chorioallantoic membrane (CAM) assay as a scalable in vivo model for studying circulating tumor cells (CTCs). Human gastrointestinal tumors spontaneously released genetically validated CTCs that were detected across multiple platforms, demonstrating that the CAM model provides an accessible tool for investigating early cancer ...
Dennis Roth, Rui P. L. Neves, Julia Geheb, Christian Ballmeyer, Nathalie Gaßmann, Kiki C. Andree, Monica Sudarsanam, Christiane Driemel, Celine Örencik, Andrè Franken, Eslam Elmaghraby, Sven H. Loosen, Roderburg Christoph, Sebastian Schoelch, Hans Neubauer, Wolfram T. Knoefel, Nikolas H. Stoecklein, Georg Fluegen   +17 more
wiley   +1 more source

A new evaluation of the rearranged non-coding control region of JC virus in patients with colorectal cancer. [PDF]

BMC Cancer
Haghi Navand A, Jalilian S, Ahmadi Angali K, Karimi Babaahmadi M, Talaiezadeh A, Makvandi M.   +5 more
europepmc   +1 more source

Extracellular matrix remodeling and immune reprogramming drive residual tumor progression of liver cancer after incomplete microwave ablation

Molecular Oncology, EarlyView.
Incomplete microwave ablation (iMWA) of liver cancer triggers a biphasic progression in residual tumors. At Day 3, the microenvironment is characterized by acute inflammatory responses and extracellular matrix (ECM) remodeling. By Day 14, a profound shift occurs toward oncogenic signal transduction and immunosuppression, marked by macrophage ...
Yu Liu, Yubei He, Nikolaus Berndt, Michael Mülleder, Kathrin Textoris‐Taube, Jing Guo, Matthias Stechele, Justus Ramtke, Shraga Nahum Goldberg, Lynn Jeanette Savic   +9 more
wiley   +1 more source