Results 51 to 60 of about 3,051,873 (249)

Organizing the interface—Plasma membrane architecture and receptor dynamics in virus‐cell interactions

FEBS Letters, EarlyView.
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley   +1 more source

Analysis of the epidemiological characteristics of foodborne botulism in Xinjiang, China from 2016 to 2024

BMC Infectious Diseases
Background This study systematically analyzes the epidemiological characteristics of foodborne botulism in Xinjiang from 2016 to 2024. Methods Data were collected from reports across Xinjiang, with all events confirmed through epidemiological ...
Amina Danai, Jia Huang, Jing Su, Weiwei Meng, Yujia Lin, Yonghe Yuan, Xin Ma   +6 more
doaj   +1 more source

Residual tail twisting in ascidian larvae is stabilized by asymmetric myofibrils that resist bilateral symmetry restoration

FEBS Letters, EarlyView.
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure, Misaki K. Nishio, Satoru Okuda, Kohji Hotta   +3 more
wiley   +1 more source

The human gut microbiome across the life course

FEBS Letters, EarlyView.
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero, Basak Bahcivanci, Antonietta Hayhoe, Animesh Acharjee, Ezgi Özkurt   +4 more
wiley   +1 more source

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

FEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto, Masatomo So, Ayako Furukawa, Kenji Sugase   +3 more
wiley   +1 more source

Genetic characteristics of two of human rhinovirus A49 detected in Ningxia Hui Autonomous Region in 2021: a whole-genome analysis

Zhongguo gonggong weisheng
ObjectiveTo analyze genetic characteristics and variation in whole-genome sequence of two human rhinovirus (HRV) A49 strains detected in Yinchuan city, Ningxia Hui Autonomous Region in 2021.
Yanyan SU, Yanxue LI, Xinning WANG, Jianxin PEI, Zhonglan WU, Xueping MA, Yinhao ZHANG   +6 more
doaj   +1 more source

Drug resistance patterns of Mycobacterium tuberculosis complex and risk factors associated with multidrug-resistant tuberculosis in the upper southern part of Thailand

Epidemiology, Biostatistics and Public Health, 2019
Background: this study aimed to assess the drug resistant pattern of Mycobacterium tuberculosis complex (MTBC) and the risk factors associated to multidrug-resistant tuberculosis cases (MDR-TB) in upper part of southern Thailand.
Tum Boonrod, Lily Ingsrisawang, Petchawan Pungrassami, Supattra Sengsong, Arisa Bromnavej, Pinkamon Waseewiwat, Natthapakam Sreevijit, Bunrit Bunsanong, Chusri Bunsin   +8 more
doaj   +1 more source

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

FEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa, Shinya Sugimoto, Toshiro Sato   +2 more
wiley   +1 more source

Epidemiological characteristics of Japanese encephalitis in Guangxi Zhuang Autonomous Region from 2012 to 2023

Zhongguo gonggong weisheng
ObjectiveTo analyze the epidemiological characteristics of Japanese encephalitis (JE) in Guangxi Zhuang Autonomous Region from 2012 to 2023 and provide scientific evidence for developing JE prevention and control strategies. MethodsJE incidence data from
Jiagui CHEN, Qiuyun DENG, Jinfa DU, Rencong YANG, Shiyi CHEN, Liang LIANG, Ming GAN, Lili DENG   +7 more
doaj   +1 more source

The superpowers of imprinting control regions

Genome Research
Genomic imprinting is a specialized mechanism of transcriptional regulation whereby approximately 200 mammalian genes are expressed monoallelically according to their parental origin. This crucial developmental process is primarily controlled by discrete cis -regulatory elements known as ...
Montibus, Bertille, Court, Franck, Arnaud, Philippe   +2 more
openaire   +3 more sources