Results 111 to 120 of about 17,598,917 (302)

Transcriptional profiling of circulating extracellular vesicles from prebiopsy prostate cancer patients

open access: yesMolecular Oncology, EarlyView.
RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner   +14 more
wiley   +1 more source

Sociology of Leisure: Risk and Leisure RLO

open access: yes, 2010
This RLO is part of “Sociology of Leisure” course. The module discusses some major features of current leisure patterns, but these activities are also central to modern life itself and thus have interests for sociologists.
Dr Dave Harris, MARJON
core  

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

open access: yesMolecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary   +1 more
wiley   +1 more source

Hedging price risk under production flexibility and basis risk

open access: yes, 1999
A également fait l'objet d'une présentation au Southern Risk and Insurance Association, les 21-23/11/1999 à Orlando (USA) Diffusion du document : INRA Unité d'Economie et Sociologie rurales rue Adolphe Bobierre CS 61103 35011 Rennes Cedex (FRA)A ...
Mahul, Olivier   +1 more
core   +1 more source

Farmland Control Decisions under Different Intertemporal Risk Behavioral Constructs [PDF]

open access: yes
Simulation-optimization techniques are employed to analyze changes in farmland control arrangements as a result of using different constructs of intertemporal risk behavior.
Escalante, Cesar L.   +1 more
core  

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska   +13 more
wiley   +1 more source

Stimulator of interferon genes agonist augmented antitumor immunity of osimertinib in Egfr‐mutated lung cancer

open access: yesMolecular Oncology, EarlyView.
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura   +19 more
wiley   +1 more source

Development of Smallpox Antibody Testing and Surveillance Following Smallpox Vaccination in the Republic of Korea

open access: yesVaccines
Background: Despite its global eradication in 1977, smallpox remains a concern owing to its potential as a biological agent, thereby prompting the ongoing development and utilization of its vaccine.
Hwachul Shin   +4 more
doaj   +1 more source

Sovereign risk and the pricing of corporate credit default swaps

open access: yes, 2015
Investigation about the impact of sovereign risk on the pricing of corporate credit ...
Westerfeld, Simone   +2 more
core   +1 more source

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