Results 141 to 150 of about 7,697,986 (294)
Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers
Molecular Oncology, EarlyView.This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel +6 more
wiley +1 more source
Políticas públicas, trabajo y criminalidad: algunas pistas desde la teoría sociológica del riesgo
Revista de la Facultad de Derecho, 2014 Cuando un criminólogo se debe abocar a la búsqueda de factores explicativosdel delito, no debería sorprender que uno de los primeros en aparecer fuera el desempleo.O al menos, en caso contrario, razonablemente esperaríamos que justificara su exclusión ...
Francisco Pucci, Nicolás Trajtenberg
doaj
Molecular Oncology, EarlyView.Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova +25 more
wiley +1 more source
Major neurotransmitter systems in dorsal hippocampus and basolateral amygdala control social recognition memory. [PDF]
Proc Natl Acad Sci U S A, 2016 Garrido Zinn C +5 more
europepmc +1 more source
Molecular Oncology, EarlyView.Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano +6 more
wiley +1 more source
El pastor, el doctor y el Big Data
Revista Teknokultura, 2014 La consolidación de Internet como espacio de relación global implica que la subjetivación política de la vigilancia automatizada adquiera especial relevancia a la hora de comprender los mecanismos de control social en nuestra cultura.
Alejandro Segura Vázquez
doaj
A study of dyadic interdependence of control, social participation and occupation of adults who use long-term care services and their carers. [PDF]
Qual Life Res, 2017 Rand S, Forder J, Malley J.
europepmc +1 more source
Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma
Molecular Oncology, EarlyView.Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra +6 more
wiley +1 more source
Social media fatigue in nursing students: the role of self-control, social comparison, and fear of missing out. [PDF]
BMC PsycholParvizi A +5 more
europepmc +1 more source
Molecular Oncology, EarlyView.Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson +9 more
wiley +1 more source