Results 151 to 160 of about 28,382,436 (368)
Transcriptome‐wide analysis of circRNA and RBP profiles and their molecular relevance for GBM
CircRNAs are differentially expressed in glioblastoma primary tumors and might serve as therapeutic targets and diagnostic markers. The investigation of circRNA and RNA‐binding proteins (RBPs) interactions shows that distinct RBPs play a role in circRNA biogenesis and function.
Julia Latowska‐Łysiak+14 more
wiley +1 more source
This study investigates an alternative approach to reactivating the oncosuppressor p53 in cancer. A short peptide targeting the association of the two p53 inhibitors, MDM2 and MDM4, induces an otherwise therapeutically active p53 with unique features that promote cell death and potentially reduce toxicity towards proliferating nontumor cells.
Sonia Valentini+10 more
wiley +1 more source
Psycho-Social Effects of Home Care: Results of a Randomized Controlled Trial [PDF]
Lowell W. Gerson, A. F. E. BERRY
openalex +1 more source
Combining melting curve analysis enhances the multiplexing capability of digital PCR. Here, we developed a 14‐plex assay to simultaneously measure single nucleotide mutations and amplifications of KRAS and GNAS, which are common driver genes in pancreatic cancer precursors. This assay accurately quantified variant allele frequencies in clinical samples
Junko Tanaka+10 more
wiley +1 more source
Este articulo analiza la forma en que el Plan de Desarrollo "Cambio para contruir la Paz" trata el sistema de seguridad social y su interpretacion sobre las causas de la exclusion social. El plan carece de una vision de conjunto del sistema por cuanto no
Rodríguez Salazar Oscar
doaj
Deviance and Social Control in Chinese Society [PDF]
Amy Auerbacher Wilson+2 more
openalex +1 more source
Exploration of heterogeneity and recurrence signatures in hepatocellular carcinoma
This study leveraged public datasets and integrative bioinformatic analysis to dissect malignant cell heterogeneity between relapsed and primary HCC, focusing on intercellular communication, differentiation status, metabolic activity, and transcriptomic profiles.
Wen‐Jing Wu+15 more
wiley +1 more source
Este trabalho analisa o exercício do controle social no Brasil, a partir do debate geral que o estimulou e do contexto interno que culminou na criação de espaços institucionalizados para sua aplicação. Tem-se como objetivo avaliar o exercício do controle
Claudio Gurgel, Agatha Justen
doaj