Results 61 to 70 of about 28,382,436 (368)

Interaction vesicles as emerging mediators of host‐pathogen molecular crosstalk and their implications for infection dynamics

open access: yesFEBS Letters, EarlyView.
Interaction extracellular vesicles (iEVs) are hybrid vesicles formed through host‐pathogen communication. They facilitate immune evasion, transfer pathogens' molecules, increase host cell uptake, and enhance virulence. This Perspective article illustrates the multifunctional roles of iEVs and highlights their emerging relevance in infection dynamics ...
Bruna Sabatke   +2 more
wiley   +1 more source

The role of the police and economic order in San Miguel de Tucumán at the end of the XVIII century. Alleged offenders, hoarders and monopolists.

open access: yesHistoria y Memoria, 2014
This paper seeks to address the problem of the emergence of role of the police at Río de la Plata, as part of the consequences of enlightened thought at the end of the XVIII century.
Romina Noemí Zamora
doaj   +1 more source

ACCESS CONTROL IN A SOCIAL NETWORKING ENVIRONMENT [PDF]

open access: yes, 2013
Collecting users into groups is a common activity in social networking sites such as Facebook, Google groups, Yahoo groups and many other web applications. This project explores access control techniques for dynamically created groups. The starting point
Perepa, Mallika
core   +1 more source

Working-class royalty: bees beat the caste system [PDF]

open access: yes, 2005
The struggle among social classes or castes is well known in humans. Here, we show that caste inequality similarly affects societies of ants, bees and wasps, where castes are morphologically distinct and workers have greatly reduced reproductive ...
Camargo J.M.F   +9 more
core   +2 more sources

Decoding the dual role of autophagy in cancer through transcriptional and epigenetic regulation

open access: yesFEBS Letters, EarlyView.
Transcriptional and epigenetic regulation controls autophagy, which exerts context‐dependent effects on cancer: Autophagy suppresses tumorigenesis by maintaining cellular homeostasis or promotes tumor progression by supporting survival under stress. In this “In a Nutshell” article, we explore the intricate mechanisms of the dual function of autophagy ...
Young Suk Yu, Ik Soo Kim, Sung Hee Baek
wiley   +1 more source

The moderator-mediator variable distinction in social psychological research: conceptual, strategic, and statistical considerations.

open access: yesJournal of Personality and Social Psychology, 1986
In this article, we attempt to distinguish between the properties of moderator and mediator variables at a number of levels. First, we seek to make theorists and researchers aware of the importance of not using the terms moderator and mediator ...
R. M. Baron, D. Kenny
semanticscholar   +1 more source

A stepwise emergence of evolution in the RNA world

open access: yesFEBS Letters, EarlyView.
How did biological evolution emerge from chemical reactions? This perspective proposes a gradual scenario of self‐organization among RNA molecules, where catalytic feedback on random mixtures plays the central role. Short oligomers cross‐ligate, and self‐assembly enables heritable variations. An event of template‐externalization marks the transition to
Philippe Nghe
wiley   +1 more source

La lucha contra la corrupción en Colombia como herramienta para un control social exacerbado

open access: yesEstudios de Derecho, 2007
Desde que existe sociedad existe control social. Bajo esta premisa, al construir un marco teórico que dé cuenta de las variables que dan origen a la lucha contra la corrupción en Colombia, el análisis de las dinámicas dadas entre los procesos de esa ...
Mauricio Hernando Aguirre Giraldo
doaj  

Modifications in FLAP's second cytosolic loop influence 5‐LOX interaction, inhibitor binding, and leukotriene formation

open access: yesFEBS Letters, EarlyView.
The enzyme 5‐lipoxygenase (5‐LOX) catalyzes the first step in the biosynthesis of leukotrienes (LTs) involved in inflammatory pathophysiology. After cellular stimulation, 5‐LOX translocates to the nucleus, interacting with the 5‐LOX‐activating protein (FLAP) to form LTA4 from arachidonic acid (AA).
Erik Romp   +5 more
wiley   +1 more source

Economic Accountability in Central America La accountability económica en Centroamérica

open access: yesJournal of Politics in Latin America, 2009
Representative democracy hinges upon the notion of accountability. We examine the mediating effects of political context on economic accountability in a hostile environment – the developing democracies of Central America.
Gregg B. Johnson   +1 more
doaj  

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