Results 71 to 80 of about 7,697,986 (294)
La buena marcha de los asuntos públicos
Revista Eurolatinoamericana de Derecho Administrativo, 2014 El artículo analiza el tema del buen gobierno y buena administración de las instituciones públicas bajo la perspectiva del control social. La cuestión es examinada bajo la perspectiva de los derechos fundamentales del ciudadano y los derechos humanos ...
Pablo Ángel Gutiérrez Colantuono
doaj +1 more source
Tau acetylation at K331 has limited impact on tau pathology in vivo
FEBS Letters, EarlyView.We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source
El Control Social, la Familia y las Mujeres
Revista de la Facultad de Derecho, 2014 Aproximación a la noción de control social. Evolución de la concepción del control social. juicio crítico. Un punto de vista clarificador. Grupo social. Particularidades. Las élites.
Mariana Malet Vázquez
doaj
Colonialismo, deportación de cubanos y raza en tiempos de paz (1864-1867)
Revista de Indias, 2019 El presente trabajo examina como a partir de 1864, siendo Capitán general de Cuba Domingo Dulce, comenzó una política de deportaciones de delincuentes e individuos considerados de «mal vivir».
Juan Luis Bachero Bachero
doaj +1 more source
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
Historia Regional, 2018 A partir de la reconstrucción del comportamiento delictivo de dos sujetos del sur santafesino durante el transcurso de la segunda mitad del siglo XIX, nos proponemos analizar las formas de acción que se llevaron a cabo desde el Estado Provincial a los ...
Jose Miguel Larker
doaj
FEBS Letters, EarlyView.This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel +13 more
wiley +1 more source
Mechanisms of alignment: shared control, social cognition and metacognition. [PDF]
Philos Trans R Soc Lond B Biol Sci, 2023 Gandolfi G, Pickering MJ, Garrod S.
europepmc +1 more source
PENGARUH LONELINESS DAN SELF-CONTROL TERHADAP INSTAGRAM SOCIAL MEDIA DISORDER PADA EMERGING ADULTHOOD [PDF]
Inappropriate use of Instagram social media and the habit of accessing it excessively can have bad effects, one of which is addiction, mental health disorders (loneliness), and disturbances in self-control, which are categorized as social media disorder.
Nuwada, Tiara Putri
core
FEBS Letters, EarlyView.Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source