Results 111 to 120 of about 2,605,132 (291)
Molecular Oncology, EarlyView.Loss of the frequently mutated chromatin remodeler ARID1A, a subunit of the SWI/SNF cBAF complex, results in less open chromatin, alternative splicing, and the failure to stop cells from progressing through the cell cycle after DNA damage in bladder (cancer) cells. Created in BioRender. Epigenetic regulators, such as the SWI/SNF complex, with important
Rebecca M. Schlösser +11 more
wiley +1 more source
Цифрова фільтрація, спектральний аналіз та оптимізація точності вимірювань у мобільній системі контролю [PDF]
, 2012 В настоящее время воплощения инженерных методов защиты от помех позволяет ис- пользовать на практике сотни различных решений. Эта ситуация создала проблему трудоем- кого плохо формализованного обоснованного выбора одного из этих решений.
Лопатін, В.В.
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Molecular Oncology, EarlyView.Comprehensive analysis of genomic mutations, gene expression, DNA methylation, and pathway analysis of TCGA data was carried out to define cancer types in which proteasome subunits expression is associated with worse survival. Albeit the effect of specific proteasome subunits on cellular function, the main role of the proteasome is better evaluated ...
Ruba Al‐Abdulla +5 more
wiley +1 more source
Molecular Oncology, EarlyView.This study develops a semi‐supervised classifier integrating multi‐genomic data (1404 training/5893 validation samples) to improve homologous recombination deficiency (HRD) detection in breast cancer. Our method demonstrates prognostic value and predicts chemotherapy/PARP inhibitor sensitivity in HRD+ tumours.
Rong Zhu +12 more
wiley +1 more source
Experiences with the design and implementation of flutter suppression systems [PDF]
, 1984 Research efforts aim at flutter suppression are discussed. The application of active controls technology to reduce the aeroelastic response of aircraft structures is discussed.
Abel, I., Newsom, J. R.
core +1 more source
A nucleotide‐independent, pan‐RAS‐targeted DARPin elicits anti‐tumor activity in a multimodal manner
Molecular Oncology, EarlyView.We report a Designed Ankyrin Repeat Protein that binds and inhibits RAS proteins, which serve as central cell signaling hubs and are essential for the progression of many cancers. Its unique feature is that it does not discriminate between different RAS isoforms or mutations and is capable of binding to RAS in both its active (GTP‐bound) and inactive ...
Jonas N. Kapp +13 more
wiley +1 more source
The Methods for Synthesis and Analysis Controlled Time Delay System with Required Damping Factor
, 2012 D-decomposition method in the area of relative stability, developed from Loo [7] in order to separate constant time settling area in parametric space which ensures the system having predefined settling time.[4]. This paper develops the methods for synthesis and analysis of controlled-loop system with proportional regulator for transport and dosing ...
Đorđević, Vladimir, Brašić, Vesna
openaire +1 more source
Large space structure damping design [PDF]
Several FORTRAN subroutines and programs were developed which compute complex eigenvalues of a damped system using different approaches, and which rescale mode shapes to unit generalized mass and make rigid bodies orthogonal to each other.
Haviland, J. K., Pilkey, W. D.
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EMT‐associated bias in the Parsortix® system observed with pancreatic cancer cell lines
Molecular Oncology, EarlyView.The Parsortix® system was tested for CTC enrichment using pancreatic cancer cell lines with different EMT phenotypes. Spike‐in experiments showed lower recovery of mesenchymal‐like cells. This was confirmed with an EMT‐inducible breast cancer cell line.
Nele Vandenbussche +8 more
wiley +1 more source
, 2020 New methods are developed for the stabilization of a linear system with general time-varying distributed delays existing at the system's states, inputs and outputs.
Feng, Qian +2 more
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