Results 101 to 110 of about 2,699,619 (276)
Synthesis of aircraft structures using integrated design and analysis methods [PDF]
A systematic research is reported to develop and validate methods for structural sizing of an airframe designed with the use of composite materials and active controls. This research program includes procedures for computing aeroelastic loads, static and
Goetz, R. C. +1 more
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Experiences with the design and implementation of flutter suppression systems [PDF]
, 1984 Research efforts aim at flutter suppression are discussed. The application of active controls technology to reduce the aeroelastic response of aircraft structures is discussed.
Abel, I., Newsom, J. R.
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Molecular Oncology, EarlyView.Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat +8 more
wiley +1 more source
Optimal and Robust Design of Integrated Control and Diagnostic Modules [PDF]
, 1994 The problem of designing an integrated control and diagnostic module is considered. The four degree of freedom controller is recast into a general framework wherein results from optimal and robust control theory can be easily implemented. For the case of
Morari, Manfred, Tyler, Matthew L.
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Correlation of the differential expression of PIK3R1 and its spliced variant, p55α, in pan‐cancer
Molecular Oncology, EarlyView.PIK3R1 undergoes alternative splicing to generate the isoforms, p85α and p55α. By combining large patient datasets with laboratory experiments, we show that PIK3R1 spliced variants shape cancer behavior. While tumors lose the protective p85α isoform, p55α is overexpressed, changes linked to poorer survival and more pronounced in African American ...
Ishita Gupta +10 more
wiley +1 more source
Behavior sensitivities for control augmented structures [PDF]
During the past few years it has been recognized that combining passive structural design methods with active control techniques offers the prospect of being able to find substantially improved designs.
Lust, R. V. +2 more
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Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
Molecular Oncology, EarlyView.Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley +5 more
wiley +1 more source
Robust ℋ2 Performance: Guaranteeing Margins for LQG Regulators [PDF]
, 1995 This paper shows that ℋ2 (LQG) performance specifications can be combined with structured uncertainty in the system, yielding robustness analysis conditions of the same nature and computational complexity as the corresponding conditions for ℋ ...
Paganini, Fernando
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