Results 81 to 90 of about 2,699,619 (276)
FEBS Letters, EarlyView.This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel +13 more
wiley +1 more source
On robust stability of switched homogeneous systems
IET Control Theory & Applications, 2021 This paper analyses the robust stability of a class of homogeneous systems where a relation among the high‐order term, the decay rate and the domain of attraction of the system is explicitly established.
Hao Yang +3 more
doaj +1 more source
Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation
FEBS Letters, EarlyView.Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz +11 more
wiley +1 more source
Event‐triggered control of singularly perturbed linear system with DoS attacks
IET Control Theory & Applications, 2021 This paper presents the event‐triggered control problem of linear singularly perturbed systems in the presence of denial‐of‐service attacks. To save the communication and computing resources, event‐triggered mechanisms in two transmission channels are ...
Xiang Ren, Fei Hao
doaj +1 more source
Effects of heme oxygenase isozymes on Leydig cells steroidogenesis [PDF]
, 2009 In the present study, we demonstrate the expression of heme oxygenase (HO) isozymes, HO-1 and HO-2 (listed as HMOX1 and HMOX2 in the MGI Database), in MA-10 Leydig tumor cells and its effect on steroidogenesis. The well-known HO inducer, hemin, increased
Besio Moreno, Marcos Alberto +6 more
core +1 more source
An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane
FEBS Letters, EarlyView.Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa +3 more
wiley +1 more source
Evolutionary design of a full-envelope full-authority flight control system for an unstable high-performance aircraft [PDF]
, 2011 The use of an evolutionary algorithm in the framework of H1 control theory is being considered as a means for synthesizing controller gains that minimize a weighted combination of the infinite norm of the sensitivity function (for disturbance attenuation
Abzug M. J. +9 more
core +1 more source
pH‐mediated activation of the lysosomal arginine sensor SLC38A9
FEBS Letters, EarlyView.Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley +1 more source
Modern CACSD using the Robust-Control Toolbox [PDF]
The Robust-Control Toolbox is a collection of 40 M-files which extend the capability of PC/PRO-MATLAB to do modern multivariable robust control system design.
Chiang, Richard Y., Safonov, Michael G.
core +1 more source
Efficient numerical methods for aeroelastic analysis of wing-propeller configuration compound helicopters [PDF]
, 2017 Efficient numerical methods for time-domain aeroelastic analysis of a wing structure under a propeller-wing configuration is described in the paper. A linear beam model with deformable elastic axis under torsion and flapping is considered to simulate a ...
Anobile, Alessandro +2 more
core