Results 181 to 190 of about 9,826,001 (249)

Phase coupling between eye and brain pulsations is bidirectional and modulated by the parasympathetic system – An fMREye study

Acta Ophthalmologica, EarlyView.
Abstract Purpose Physiological pulsations driven by cardiac, respiratory, and vasomotor activity are essential for solute transport within perivascular and perineural cerebrospinal fluid (CSF) pathways that support brain and eye clearance systems. Previous studies have shown that parasympathetic blockade significantly reduces ocular pulsation power and
Ebrahimi Seyed‐Mohsen, Väyrynen Tommi, Huotari Niko, Saarela Ville, Honkamo Marja, Helakari Heta, Järvelä Matti, Korhonen Vesa, Raitamaa Lauri, Kiviniemi Vesa   +9 more
wiley   +1 more source

Beyond the numbers: hypotension, algorithms, and the elusive promise of renal protection. [PDF]

Ann Transl Med
da Hora Passos R, Melo RH, Rabello Filho R, Zawadzki B, Hamzaoui O.   +4 more
europepmc   +1 more source

Optic nerve head blood flow autoregulation during isometric exercise in primary open‐angle glaucoma assessed by laser speckle flowgraphy

Acta Ophthalmologica, EarlyView.
Abstract Purpose To assess optic nerve head blood flow (ONHBF) autoregulation in patients with early‐ to moderate‐stage primary open‐angle glaucoma (POAG) and age‐ and sex‐matched healthy controls using laser speckle flowgraphy (LSFG) and isometric handgrip exercise.
Theresa Lindner, Viktoria Pai, Patrick Janku, Nikolaus Hommer, Anton Hommer, Liudmyla Petric, Ulrich Graf, Leopold Schmetterer, Gerhard Garhöfer, Doreen Schmidl   +9 more
wiley   +1 more source

[Association between hemodynamic parameters, insulin resistance, and body composition in primary care]. [PDF]

Aten Primaria
Mill Ferreyra EÓ, Verde de García RL, Azuara Azuara M, Zarza Fernández AM, Rodríguez Arce M, Pérez Coca C.   +5 more
europepmc   +1 more source

Death Determination, the Dying Process and the Dead Donor Rule: A Critical Analysis of the Italian 20‐Minute No‐Touch Period in Controlled Donation After Circulatory Determination of Death

Bioethics, EarlyView.
ABSTRACT In Italy, controlled Donation after Circulatory Determination of Death (cDCDD) requires a 20‐min no‐touch period documented by continuous electrocardiographic monitoring. Since Italian law adopts a single brain‐based definition of death, this procedure serves as an indirect determination of the irreversible cessation of all brain functions ...
Lucia Craxì
wiley   +1 more source

Analysis of the clinical effect of dexmedetomidine hydrochloride for sedation before cosmetic suturing of emergency facial trauma in children. [PDF]

Front Surg
Gao W, Song X, Feng Y, Liu C.
europepmc   +1 more source

Effect of atropine on time to cardiac arrest in hypoxic bradycardia: a randomised cross-over study in a porcine apnoea model. [PDF]

BJA Open
Pařízek T, Waldauf P, Kalina M, Kurzová Z, Odstrčilová I, Hunák J, Freml J, Dvořák R, Peřan D, Vlková A, Duška F.   +10 more
europepmc   +1 more source

An intracellular recombinant single‐chain variable antibody fragment as a new class of phosphodiesterase type 5 inhibitors

British Journal of Pharmacology, EarlyView.
Background and Purpose Cyclic guanosine monophosphate (cGMP) is a ubiquitous second messenger involved in human (patho‐)physiology. Phosphodiesterase 5 (PDE5) is a major cGMP hydrolyzing enzyme in many cell types including vascular smooth muscle cells (VSMCs). Several highly selective PDE5 inhibitors are in clinical use. However, there are currently no
Kürsat Kirkgöz, Sophie Sprenger, Olga Schweigert, Sanika Mohagaonkar, Matti Walsdorff, Tanja Zeller, Filip Berisha, Viacheslav O. Nikolaev, Sergei D. Rybalkin   +8 more
wiley   +1 more source

Primary Vascular Dysregulation in Normal-Tension Glaucoma: Pathophysiology and Management. [PDF]

Cureus
Banerjee A, Sarangi PK.
europepmc   +1 more source

Cardiovascular toxicity from immune checkpoint inhibitor therapy: an inflammatory continuum

British Journal of Pharmacology, EarlyView.
Immune checkpoint inhibitor (ICI) therapy has markedly improved outcomes in advanced malignancies but has also revealed a distinct spectrum of cardiovascular immune‐related adverse events. Myocarditis represents the most severe manifestation, while non‐inflammatory left ventricular dysfunction and vascular inflammation have emerged as additional ...
Fabrice Reyes, Florian Buehning, Tobias Lerchner, Julia Vogel, Raluca I. Mincu, Matthias Totzeck, Tienush Rassaf, Lars Michel   +7 more
wiley   +1 more source