Results 221 to 230 of about 1,396,590 (327)

Endogenous Amplification of Apoptosis via p53 Regulation using a Cascade Nanocatalytic Medicine

open access: yesAdvanced Science, EarlyView.
An engineered MOF nanomedicine (MAL) triggers cascade nanocatalysis in tumors, converting H2O2 and L‐Arg into cytotoxic peroxynitrite. This induces DNA damage, activates the p53 pathway, and amplifies mitochondrial apoptosis via the BAX/Bcl‐2/Caspase‐3 axis, effectively inhibiting colorectal cancer growth with high biocompatibility.
Tan Wu   +8 more
wiley   +1 more source

Educational intervention with a booklet on syphilis for women in situations of sexual vulnerability: a quasi-experimental study. [PDF]

open access: yesRev Lat Am Enfermagem
Estumano VKC   +6 more
europepmc   +1 more source

Factors associated with the time taken for diagnosis of amyotrophic lateral sclerosis (ALS) in Brazil. An online population-based inquiry. [PDF]

open access: yesRev Neurol, 2023
Pereira-Elizeu AV   +6 more
europepmc   +1 more source

MVP Inhibits Influenza A Virus‐Induced Ferroptosis by Targeting IRF1 and Increasing FSP1 Activity

open access: yesAdvanced Science, EarlyView.
During IAV infection, MVP inhibits IRF1 polyubiquitination, thereby relieving IRF1‐mediated transcriptional inhibition of FSP1. Consequently, this leads to an upregulation of FSP1 expression, thereby reinforcing the inhibition of ferroptosis. In addition, the MVP can promote myristoylation and ubiquitination of FSP1, enabling its membrane localization ...
Yingbo Chen   +12 more
wiley   +1 more source

[Submicroscopic <i>Plasmodium</i> spp. Infections in Febrile Patients in Togo]. [PDF]

open access: yesMed Trop Sante Int
Teou DC   +10 more
europepmc   +1 more source

Modulating Local Electronic Structure via Cluster Engineering on Cobalt Phosphide for Efficient Water/Seawater Splitting

open access: yesAdvanced Science, EarlyView.
The heterostructure benefits from the high dispersion of FeOx nanoclusters on the porous CoxP substrate, while the interfacial bonds Fe‐O‐Co enhance charge transport and redistribution, resulting in excellent oxygen evolution reaction performance and strong potential for practical applications.
Cheng Gong   +11 more
wiley   +1 more source

Maternal mortality: protocol of a study integrated to the Birth in Brazil II survey. [PDF]

open access: yesCad Saude Publica
Gama SGND   +11 more
europepmc   +1 more source

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