Results 121 to 130 of about 18,844,670 (344)

Behaviour near the boundary for solutions of elasticity systems

open access: yesElectronic Journal of Differential Equations, 1997
In this article we study the behaviour near the boundary for weak solutions of the system $$ u''-muDelta u-(lambda +mu )abla (alpha (x),{ m div}, u)=h,, $$ with $u(x,t)=0$ on the boundary of a domain $Omegain {R}^n$, and $u(x,0)=u^0$, $u'(x,0)=u^1$ in ...
Valeria N. Domingos Cavalcanti
doaj  

Comparing self‐reported race and genetic ancestry for identifying potential differentially methylated sites in endometrial cancer: insights from African ancestry proportions using machine learning models

open access: yesMolecular Oncology, EarlyView.
Integrating ancestry, differential methylation analysis, and machine learning, we identified robust epigenetic signature genes (ESGs) and Core‐ESGs in Black and White women with endometrial cancer. Core‐ESGs (namely APOBEC1 and PLEKHG5) methylation levels were significantly associated with survival, with tumors from high African ancestry (THA) showing ...
Huma Asif, J. Julie Kim
wiley   +1 more source

A large‐scale retrospective study in metastatic breast cancer patients using circulating tumour DNA and machine learning to predict treatment outcome and progression‐free survival

open access: yesMolecular Oncology, EarlyView.
There is an unmet need in metastatic breast cancer patients to monitor therapy response in real time. In this study, we show how a noninvasive and affordable strategy based on sequencing of plasma samples with longitudinal tracking of tumour fraction paired with a statistical model provides valuable information on treatment response in advance of the ...
Emma J. Beddowes   +20 more
wiley   +1 more source

Soft‐switching multiport DC‐DC converter for PV/EV applications with a bidirectional port

open access: yesIET Renewable Power Generation
This paper proposes a new soft‐switching bidirectional multiport DC/DC converter for PV/EV applications. The proposed topology is capable of using several different sources simultaneously.
Mohammad Maalandish   +4 more
doaj   +1 more source

Multidimensional OMICs reveal ARID1A orchestrated control of DNA damage, splicing, and cell cycle in normal‐like and malignant urothelial cells

open access: yesMolecular Oncology, EarlyView.
Loss of the frequently mutated chromatin remodeler ARID1A, a subunit of the SWI/SNF cBAF complex, results in less open chromatin, alternative splicing, and the failure to stop cells from progressing through the cell cycle after DNA damage in bladder (cancer) cells. Created in BioRender. Epigenetic regulators, such as the SWI/SNF complex, with important
Rebecca M. Schlösser   +11 more
wiley   +1 more source

New Study on the Controllability of Non-Instantaneous Impulsive Hilfer Fractional Neutral Stochastic Evolution Equations with Non-Dense Domain

open access: yesFractal and Fractional
The purpose of this work is to investigate the controllability of non-instantaneous impulsive (NII) Hilfer fractional (HF) neutral stochastic evolution equations with a non-dense domain. We construct a new set of adequate assumptions for the existence of
Gunasekaran Gokul   +4 more
doaj   +1 more source

Multi‐omic characterization of consensus molecular subtype 1 (CMS1) colorectal cancer with dampened immune response improves precision medicine

open access: yesMolecular Oncology, EarlyView.
This study highlights the importance of multi‐omic analyses in characterizing colorectal cancers. Indeed, our analysis revealed a rare CMS1 exhibiting dampened immune activation, including reduced PD‐1 expression, moderate CD8+ T‐cell infiltration, and suppressed JAK/STAT pathway.
Livia Concetti   +10 more
wiley   +1 more source

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