Results 51 to 60 of about 3,451,749 (250)

Perfectionism and workaholism in employees: The role of work motivation [PDF]

, 2013
Even though it has been over 20 years since Spence and Robbins (1992) first showed perfectionism and workaholism to be closely related, the relationship between perfectionism and workaholism is still under-researched.
Stoeber, Joachim, Davis, Charlotte R., Townley, Jessica   +2 more
core   +1 more source

Castration‐resistant prostate cancer cells are addicted to the high activity of cyclin‐dependent kinase 2

Molecular Oncology, EarlyView.
We show that emergence of castration‐resistant prostate (CRPC) is associated with significant upregulation of cyclins that positively regulate cyclin‐dependent kinase 2 (CDK2) and concomitant downregulation of CDK4 cyclins. This renders CRPC cells dependent on the high activity of CDK2, and CDK2 inhibitors synergistically sensitize CRPC cells to both ...
Joyeeta Chatterjee, Alessia Marin, Shivani Yalala, Harri M. Itkonen   +3 more
wiley   +1 more source

Navigating AI integration in higher education: assessing the impact of assessment formats and motivation types on students’ AI usage intentions

Cogent Education
Recent advances in artificial intelligence (AI) are reshaping teaching and learning, prompting renewed policy attention within higher education. While prior research has explored the antecedents of students’ AI usage intentions, limited attention has ...
Prince Baah-Peprah, Samuel Anokye Nyarko, Obed Opoku Afram, Bjørn-Tore Flåten, Lia Alexandra Baltador, Valentin Grecu   +5 more
doaj   +1 more source

Spatial heterogeneity of hotspot mutations and clonal relatedness in ovarian endometrioid carcinoma

Molecular Oncology, EarlyView.
Spatially resolved analysis revealed heterogeneous distributions of selected cancer‐associated mutations within ovarian endometrioid carcinomas. Shared mutations between paired endometrial and ovarian tumors supported clonal relatedness. These findings highlight the value of sampling multiple tumor regions when interpreting molecular profiles ...
Takahito Ashihara, Kosuke Murakami, Shiro Takamatsu, Akiko Kanto, Seiichi Mori, Tomoyuki Otani, Kazuko Sakai, Yasushi Kotani, Kazuto Nishio, Kaoru Abiko, Noriomi Matsumura   +10 more
wiley   +1 more source

Language of flourishing: Wellbeing literacy for motivation and emotion in higher education. [PDF]

Background: Wellbeing literacy, defined as the capability to comprehend and compose wellbeing language across contexts with intentionality, has emerged as a foundational capability for sustaining wellbeing, mental health, motivation, and academic success
Antunes, Maria Luz, Lopes, Carlos, Moniz, Maria João Vargas, Vital, Ana Paula   +3 more
core   +1 more source

A Multilevel Perspective on Self-Determination Theory: Predictors and Correlates of Autonomous and Controlled Motivation

, 2022
Based on Self-Determination Theory (SDT), we examined mediational models connecting autonomy support and self-criticism to negative affect [NA], positive affect [PA], and goal progress [GP] via autonomous and controlled motivation. Separate measures were
Shelby L. Levine, Golan Shahar, Anne Holding, Kayleigh-Ann Clegg, David Zuroff, Richard Koestner   +5 more
core   +1 more source

Importin 7 mediates the nuclear import of HIV‐1 integrase via a specific interacting interface

FEBS Open Bio, EarlyView.
HIV‐1 integrase enables viral DNA integration into the host genome. By binding to the core domain of the host protein Importin 7 via its C‐terminal domain, the integrase is transported across the nuclear membrane into the nucleus, where integration of the viral genome into host DNA takes place. This translocation is a critical step for subsequent viral
Juana Bana, Avigail Yariv, Tal Oppenheim, Hadar Amartely, Dana Reichmann, Oded Livnah   +5 more
wiley   +1 more source

Influence of parental structure and chaos on homework anxiety in elementary school students: the mediating role of homework motivation

Frontiers in Psychology
The present study aimed to examine the relationship between parental structure, parental chaos, and homework anxiety among elementary school students, as well as the mediating roles of autonomous and controlled motivation in relation to homework. A total
Jing Li, Yadong Ding
doaj   +1 more source

Evolution‐guided yeast complementation reveals functional differences in human PSPH variants

FEBS Open Bio, EarlyView.
Ancient genomes can help guide which human genetic variants are tested experimentally. This study applies that idea to PSPH, a gene involved in serine biosynthesis, and uses high‐throughput yeast complementation to compare variant function. The findings reveal measurable differences among selected alleles and illustrate the value of evolution‐guided ...
Mauricio Campa‐Álvarez, Diana Ascencio, Miguel Vallebueno‐Estrada, Eduardo González‐Orozco, Christian Eduardo Martínez‐Guerrero, Rafael Montiel, Alexander DeLuna   +6 more
wiley   +1 more source

Motivational Profiles of Medical Students of Nepalese Army Institute of Health Sciences

Journal of Nepal Health Research Council, 2018
Background: Students enter the medical study with different types of motives. Given the importance of academic motivation for good academic achievement of the students, the present study was designed to reveal the possible relationship between academic ...
Lochana Shrestha, Shambhu Nath Pant
doaj   +1 more source