Results 81 to 90 of about 3,110,857 (254)

“Activation‐Resistance Elimination” Regulation by Lanthanide/Transition Metal Ion‐Coordinated Nanostructures Intensifies Cuproptosis and Tumor Immunotherapy

open access: yesAdvanced Materials, EarlyView.
The lanthanide/transition metal ion coordination nanoparticles, La‐Cu@Lap/IWR‐1, with optimized coordination, have been proven to achieve remarkable results in realizing comprehensive tumor cuproptosis through efficient cuproptosis activation and multidimensional resistance elimination, thereby synchronously realizing the synergistic antitumor effects ...
Junrong Wang   +8 more
wiley   +1 more source

Comparison Between PPOS and GnRHa-Long Protocol in Clinical Outcome with the First IVF/ICSI Cycle: A Randomized Clinical Trial

open access: yesClinical Epidemiology, 2020
Qianwen Xi, Yu Tao, Meiting Qiu, Yun Wang, Yanping Kuang Department of Assisted Reproduction, Shanghai Ninth People’s Hospital Affiliated to JiaoTong University School of Medicine, Shanghai, People’s Republic of ChinaCorrespondence: Yun Wang;
Xi Q, Tao Y, Qiu M, Wang Y, Kuang Y
doaj  

Cross‐Scale Hierarchical Targeted Delivery System Based on Small‐Scale Magnetic Robots

open access: yesAdvanced Robotics Research, EarlyView.
This article reviews a cross‐scale hierarchical targeted delivery system that integrates magnetic continuum robots and magnetic microrobots. By combining rapid long‐range navigation with precise microscale targeting, the system overcomes key limitations of single‐scale approaches.
Junjian Zhou   +4 more
wiley   +1 more source

Individualization of treatment in controlled ovarian stimulation: myth or reality?

open access: yes, 2017
Variability in the infertile population excludes the possibility of a single approach to controlled ovarian stimulation. The modern technology has led to the development of new drugs, treatment options and quantitative methods that allow an ...
Conforti A.   +4 more
core   +1 more source

Effectiveness of progesterone-primed ovarian stimulation in assisted reproductive technology: a systematic review and meta-analysis

open access: yes, 2021
Purpose: Progestin-primed ovarian stimulation (PPOS) is a new ovarian stimulation protocol that has been used over the last decade to enhance reproductive function.
Chen, Chen   +11 more
core   +1 more source

An Anti‐Amyloidogenic Approach to Specifically Block Memory Consolidation in Mice for Therapeutic Intervention

open access: yesAdvanced Science, EarlyView.
Functional amyloid conversion of the translation regulator CPEB3 is essential for long‐term memory persistence. This study demonstrates that targeting this molecular switch with the anti‐amyloidogenic peptide QBP1 selectively blocks CPEB3 fibrillation without disrupting phase separation.
Paula López‐García   +13 more
wiley   +1 more source

Optimal Allogeneic Platelet-Rich Plasma Concentration to Improve In Vitro Maturation of Germinal Vesicle Oocytes From Women With Polyendocrine Metabolic Ovarian Syndrome: A Prospective Cohort Study

open access: yesClinical and Experimental Obstetrics & Gynecology
Background:In vitro maturation is a long-established technique used to obtain mature oocytes outside the human body. As an alternative to assisted reproductive technology (ART) protocols involving controlled ovarian stimulation (COS) followed by in vitro
Tiara Kusumaningtyas   +10 more
doaj   +1 more source

Microglial Deubiquitinase OTUD7B Stabilizes STAT3 to Promote Neuroinflammation and Cognitive Decline in Alzheimer's Disease

open access: yesAdvanced Science, EarlyView.
. ABSTRACT Neuroinflammation driven by microglial activation is a defining feature of Alzheimer's disease (AD), yet the molecular mechanisms sustaining this proinflammatory state remain unclear. Here, we identify the deubiquitinase OTUD7B as a critical regulator of microglial activation and AD pathology.
Luyao Li   +15 more
wiley   +1 more source

Comparison of Automated Anti-Müllerian Hormone Assays and Antral Follicle Count in Predicting Ovarian Response During Ovarian Stimulation

open access: yesFertility & Reproduction, 2019
Objective: Various parameters had been used to predict ovarian response. Among them, Anti-Müllerian Hormone (AMH) and antral follicle count (AFC) demonstrate the most favourable analytical and performance characteristics.
Eek Chaw Tan   +7 more
doaj   +1 more source

Is polycystic ovarian morphology related to a poor oocyte quality after controlled ovarian hyperstimulation for intracytoplasmic sperm injection? Results from a prospective, comparative study

open access: yes, 2015
International audienceTo evaluate the relationship between polycystic ovarian morphology (PCOM) and oocyte quality after controlled ovarian stimulation for intracytoplasmic sperm injection (ICSI ...
Dewailly, Didier   +8 more
core   +1 more source

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