Results 61 to 70 of about 78,340 (285)

Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin

Molecular Oncology, EarlyView.
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla, Jan Kosla, Magdalena Prechova, Lukas Frick, Patricia Bortel, Yasmin Borutzki, Andrea Bileck, Christopher Gerner, Samuel M. Meier‐Menches, Selma Osmanagic‐Myers, Martin Gregor   +10 more
wiley   +1 more source

Experimental study of the TEMPO mediated copolymerization of styrene with divinylbenzene [PDF]

, 2008
Since the discovery of controlled radical polymerization (CRP) in the early nineties (Georges et al., 1993), an ever increasing activity has been focused on the production of polymers with narrow molecular weight distributions and well-de ned ...
Costa, Mário Rui, Dias, Rolando, Gonçalves, Miguel A.D.   +2 more
core  

Organometallic mediated radical polymerization [PDF]

, 2012
Controlled radical polymerization has become increasingly important over the past decade and a half, allowing for the facile synthesis of specific macromolecular architectures with excellent control over the chemical and physical properties. This article
Allan, Laura E. N., Perry, Mitchell R., Shaver, Michael P.   +2 more
core   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

Molecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat, Aslihan Kucuk, Omer Erdogan, Samed Ozer, Bensu Kozan, Tugba Cuceli, Erkan Gumus, Evrim Cevik, Ozge Cevik   +8 more
wiley   +1 more source

Nonthermal Plasma Technology as a Versatile Strategy for Polymeric Biomaterials Surface Modification: A Review [PDF]

, 2009
In modern technology, there is a constant need to solve very complex problems and to fine-tune existing solutions. This is definitely the case in modern medicine with emerging fields such as regenerative medicine and tissue engineering.
De Geyter, Nathalie, Desmet, Tim, Dubruel, Peter, Leys, Christophe, Morent, Rino, Schacht, Etienne   +5 more
core   +1 more source

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

Molecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova, Zuzana Kozovska, Ondrej Pos, Kristina Pavlov, Sachin Gulati, Peter Makovicky, Kristina Jakic, Monika Burikova, Eva Sedlackova, Barbora Svitkova, Silvia Tyciakova, Vojtech Bystry, Nicolas Blavet, Boris Tichy, Matej Hrnciar, Jaroslav Budis, Miroslav Tomas, Peter Dubovan, Georgina Kolnikova, Veronika Repaska, Nikoleta Mojzesova, Eva Zomborska, Daniel Pindak, Michal Mego, Tomas Szemes, Miroslava Matuskova   +25 more
wiley   +1 more source

Holographic characterization of chain photopolymerization [PDF]

, 1999
A holographic characterization technique is developed in accordance with a general photopolymerization model. The technique allows detailed quantification of the chemical parameters, including their variation from the Trommsdorff effect.
Engin, D., Kewitsch, A. S., Yariv, A.
core   +1 more source

RIPK4 function interferes with melanoma cell adhesion and metastasis

Molecular Oncology, EarlyView.
RIPK4 promotes melanoma growth and spread. RIPK4 levels increase as skin lesions progress to melanoma. CRISPR/Cas9‐mediated deletion of RIPK4 causes melanoma cells to form less compact spheroids, reduces their migratory and invasive abilities and limits tumour growth and dissemination in mouse models.
Norbert Wronski, Sławomir Lasota, Ewelina Madej, Anna A. Brożyna, Małgorzata Szczygieł, Agnieszka Harazin‐Lechowska, Jan Czerbniak, Janusz Rys, Jaroslaw Czyz, Agnieszka Wolnicka‐Glubisz   +9 more
wiley   +1 more source

Synthesis of siloxane-containing epoxy polymers Patent [PDF]

, 1970
Synthesis of siloxane containing epoxy polymers with low dielectric ...
Patterson, W. J.
core   +1 more source

Thermooxidative aging of polydicyclopentadiene in glassy state [PDF]

, 2014
Thermal aging of thin films of unstabilized polydicyclopentadiene (pDCPD) at several temperatures ranging from 120 to 30 C was investigated by means of carbonyl build up by FTIR with ammonia derivatization, double bond titration, mass uptake measurement ...
LE GAC, Pierre Yves, LE GAC, Pierre Yves, RICHAUD, Emmanuel, VERDU, Jacques   +3 more
core   +3 more sources