Results 111 to 120 of about 2,358,784 (358)

CNF/p(AM-co-KAA) Semi-Interpenetrating Network Hydrogel Fertilizer Carriers for Enhanced Nutrient Use Efficiency, Water Retention, and Salt–Alkali Resistance

open access: yesGels
Developing functional agricultural materials that synchronize nutrient release, water retention, and soil amendment is crucial to advancing resource-efficient, sustainable farming systems.
Jingxuan Pan   +5 more
doaj   +1 more source

Self-immolative linkers in polymeric delivery systems [PDF]

open access: yes, 2011
There has been significant interest in the methodologies of controlled release for a diverse range of applications spanning drug delivery, biological and chemical sensors, and diagnostics.
Blencowe, Christopher A   +4 more
core   +1 more source

Tau acetylation at K331 has limited impact on tau pathology in vivo

open access: yesFEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto   +3 more
wiley   +1 more source

Influence of peach branch compost on the yield, quality of No. 9 Peach and organic matter content in the soil

open access: yesGuoshu xuebao
【Objective】Peach(Prunus persica)is native to China, and currently, China leads the world in both peach cultivation area and production. Compared with other fruit trees, peach trees grow rapidly and produce a large amount of pruning branches annually ...
GU Jialin   +9 more
doaj   +1 more source

Calpain small subunit homodimerization is robust and calcium‐independent

open access: yesFEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy   +4 more
wiley   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Design of a new type of coating for the controlled release of heparin [PDF]

open access: yes, 1997
Thrombus formation at the surface of blood contacting devices can be prevented by local release of heparin. Preferably, the release rate should be constant for prolonged periods of time.
Engbers, G.H.M.   +4 more
core   +3 more sources

A methionine‐lined active site governs carbocation stabilization and product specificity in a bacterial terpene synthase

open access: yesFEBS Letters, EarlyView.
This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel   +13 more
wiley   +1 more source

Mechanisms of burst release from pH-responsive polymeric microparticles. [PDF]

open access: yes, 2011
Microencapsulation of drugs into preformed polymers is commonly achieved through solvent evaporation techniques or spray drying. We compared these encapsulation methods in terms of controlled drug release properties of the prepared microparticles and ...
Donaldson, M   +4 more
core   +1 more source

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