Results 241 to 250 of about 1,342,903 (330)

Intein‐based modular chimeric antigen receptor platform for specific CD19/CD20 co‐targeting

Molecular Oncology, EarlyView.
CARtein is a modular CAR platform that uses split inteins to splice antigen‐recognition modules onto a universal signaling backbone, enabling precise, scarless assembly without re‐engineering signaling domains. Deployed here against CD19 and CD20 in B‐cell malignancies, the design supports flexible multi‐antigen targeting to boost T‐cell activation and
Pablo Gonzalez‐Garcia, Noelia Moares, Wenjie Yi‐He, Rosa Luna‐Espejo, Ricardo Fernandez‐Cisnal, Javier Ocaña‐Cuesta, Juan P. Muñoz‐Miranda, Antonio Gabucio, Cecilia M. Fernandez‐Ponce, Francisco Garcia‐Cozar   +9 more
wiley   +1 more source

Problems of reservoirs automatic control in flood situations

Journal of Hydrology and Hydromechanics, 2009
Nacházel Karel
doaj   +1 more source

Deep Reinforcement Learning-Based Intelligent Water Level Control: From Simulation to Embedded Implementation. [PDF]

Sensors (Basel)
Cusihuallpa-Huamanttupa K, Sacoto-Cabrera EJ, Coaquira-Castillo RJ, Utrilla Mego LW, Herrera-Levano JC, Concha-Ramos Y, Moreno-Cardenas E.   +6 more
europepmc   +1 more source

Proportional-Derivative (PD) Controller for Heuristic Rule-based Motorway Coordinated Ramp Meters

, 2018
Rui Jiang, Jinwoo Lee, Edward Chung
openalex   +2 more sources

Improving PARP inhibitor efficacy in bladder cancer without genetic BRCAness by combination with PLX51107

Molecular Oncology, EarlyView.
Clinical trials on PARP inhibitors in urothelial carcinoma (UC) showed limited efficacy and a lack of predictive biomarkers. We propose SLFN5, SLFN11, and OAS1 as UC‐specific response predictors. We suggest Talazoparib as the better PARP inhibitor for UC than Olaparib.
Jutta Schmitz, Anna L. Bartkowiak, Michael Rose, Nora Kolks, Patrick Petzsch, Vandana Solanki, Anne Stoffel, Bianca Faßbender, Leandra Lepping, Julka Volkamer, Karl Köhrer, Marc Seifert, Tokameh Mahmoudi, Tahlita C. M. Zuiverloon, Günter Niegisch, Michèle J. Hoffmann   +15 more
wiley   +1 more source

An Integrated Cyber-Physical Digital Twin Architecture with Quantitative Feedback Theory Robust Control for NIS2-Aligned Industrial Robotics. [PDF]

Sensors (Basel)
Karlova-Sergieva V, Grasiani B, Nikolova N.   +2 more
europepmc   +1 more source

Direct Torque Control using Space Vector Modulation and Dynamic Performance of the Drive, via a Fuzzy Logic Controller for Speed Regulation

, 2011
Adamidis Georgios, Zisis Koutsogiannis
openalex   +2 more sources

Cytoplasmic p21 promotes stemness of colon cancer cells via activation of the NFκB pathway

Molecular Oncology, EarlyView.
Cytoplasmic p21 promotes colorectal cancer stem cell (CSC) features by destabilizing the NFκB–IκB complex, activating NFκB signaling, and upregulating BCL‐xL and COX2. In contrast to nuclear p21, cytoplasmic p21 enhances spheroid formation and stemness transcription factor CD133.
Arnatchai Maiuthed, Kerstin Huebner, Katharina Erlenbach‐Wuensch, Chuanpit Hampel, Daniela Thalheim, Adriana Vial‐Roehe, Bodee Nutho, Susanne Merkel, Arndt Hartmann, Pithi Chanvorachote, Regine Schneider‐Stock   +10 more
wiley   +1 more source

Designing a cascaded exponential PID controller via starfish optimizer for DC motor and liquid level systems. [PDF]

Sci Rep
Izci D, Jabari M, Çelik E, Ekinci S, Bajaj M, Rubanenko O, Prokop L.   +6 more
europepmc   +1 more source

Hardware Implementation of FPIC Controllers for Discrete-Time Chaotic Systems Using LabVIEW-FPGA [PDF]

Castro Gutiérrez, Heiner, Robles Algarín, Carlos, Taborda-Giraldo, John A.   +2 more
openalex